Carbapenem-Resistant

antibiotic consumption carbapenem-resistant Pseudomonas aeruginosa bacteremia hospital infection control interventions

Journal

Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893

Informations de publication

Date de publication:
17 May 2023
Historique:
received: 26 04 2023
revised: 14 05 2023
accepted: 15 05 2023
medline: 15 6 2023
pubmed: 15 6 2023
entrez: 15 6 2023
Statut: epublish

Résumé

Carbapenem-resistant We prospectively recorded the incidence of CRPA bacteremia, antibiotic consumption, use of hand-hygiene solutions, and isolation rates of multidrug-resistant (MDR) carrier patients. The consumption of colistin, aminoglycosides, and third-generation cephalosporins decreased significantly in the total hospital and its divisions ( In our hospital, multimodal infection control interventions resulted in a significant reduction of CRPA bacteremia, mostly due to the reduction of all classes of antibiotics.

Sections du résumé

BACKGROUND BACKGROUND
Carbapenem-resistant
METHODS METHODS
We prospectively recorded the incidence of CRPA bacteremia, antibiotic consumption, use of hand-hygiene solutions, and isolation rates of multidrug-resistant (MDR) carrier patients.
FINDINGS RESULTS
The consumption of colistin, aminoglycosides, and third-generation cephalosporins decreased significantly in the total hospital and its divisions (
CONCLUSION CONCLUSIONS
In our hospital, multimodal infection control interventions resulted in a significant reduction of CRPA bacteremia, mostly due to the reduction of all classes of antibiotics.

Identifiants

pubmed: 37317288
pii: microorganisms11051315
doi: 10.3390/microorganisms11051315
pmc: PMC10220838
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

JAMA Netw Open. 2023 Feb 1;6(2):e2253806
pubmed: 36757700
J Mol Biol. 2015 Nov 20;427(23):3628-45
pubmed: 26319792
J Hosp Infect. 2022 May;123:27-33
pubmed: 35149172
Adv Ther. 2017 Apr;34(4):854-865
pubmed: 28303388
Adv Exp Med Biol. 2022;1386:117-143
pubmed: 36258071
Biotechnol Adv. 2019 Jan - Feb;37(1):177-192
pubmed: 30500353
Curr Opin Pharmacol. 2007 Jun;7(3):244-51
pubmed: 17418640
BMJ. 1998 Apr 18;316(7139):1236-8
pubmed: 9553006
Clin Microbiol Infect. 2019 May;25(5):555-561
pubmed: 30472426
Int J Mol Sci. 2021 Mar 18;22(6):
pubmed: 33803907
J Glob Antimicrob Resist. 2020 Dec;23:430-438
pubmed: 33176216
Expert Rev Anti Infect Ther. 2018 Feb;16(2):89-110
pubmed: 29310479
Drugs. 2021 Dec;81(18):2117-2131
pubmed: 34743315
Microb Drug Resist. 2022 Jul;28(7):806-818
pubmed: 35834622
Int J Infect Dis. 2019 Jul;84:153-162
pubmed: 31204003
Crit Care Res Pract. 2011;2011:416426
pubmed: 21687626
Clin Infect Dis. 2019 Nov 13;69(Suppl 7):S521-S528
pubmed: 31724045
PLoS One. 2022 Jan 14;17(1):e0261917
pubmed: 35030191
Pathogens. 2014 Apr 10;3(2):309-40
pubmed: 25437802
Antimicrob Agents Chemother. 2022 Feb 15;66(2):e0200021
pubmed: 34807753
Am J Infect Control. 2019 Aug;47(8):1035-1037
pubmed: 30732979
Infect Control Hosp Epidemiol. 2019 Sep;40(9):1056-1058
pubmed: 31232265
Eur J Clin Microbiol Infect Dis. 2022 Jan;41(1):127-132
pubmed: 34264401
Front Cell Infect Microbiol. 2022 Jul 06;12:926758
pubmed: 35873152
Appl Microbiol Biotechnol. 2020 Dec;104(24):10655-10667
pubmed: 33151366
J Hosp Infect. 2018 Aug;99(4):396-404
pubmed: 29792971
Eur J Clin Microbiol Infect Dis. 2018 Jul;37(7):1211-1220
pubmed: 29644540
Antimicrob Resist Infect Control. 2020 Jan 3;9(1):3
pubmed: 31911831
Syst Rev. 2017 Dec 13;6(1):256
pubmed: 29237496
J Microbiol Immunol Infect. 2023 Apr;56(2):337-343
pubmed: 36210318

Auteurs

Amalia Papanikolopoulou (A)

Clinical Pharmacology Department, Athens Medical Center, 5-7 Distomou Str., 15125 Marousi, Greece.

Panagiotis Gargalianos-Kakolyris (P)

Clinical Infectious Diseases Department, Athens Medical Center, 1 Delfon Str., 15125 Marousi, Greece.

Athina Stoupis (A)

Clinical Infectious Diseases Department, Athens Medical Center, 1 Delfon Str., 15125 Marousi, Greece.

Nikos Moussas (N)

Clinical Infectious Diseases Department, Athens Medical Center, 1 Delfon Str., 15125 Marousi, Greece.

Anastasia Pangalis (A)

Biopathology Department, Athens Medical Center, 5-7 Distomou Str., 15125 Marousi, Greece.

Kalliopi Theodoridou (K)

Department of Microbiology, School of Medicine, National and Kapodistrian University of Athens, 75 Mikras Asias Str., 11527 Athens, Greece.
Department of Microbiology, Andreas Syggros Hospital for Skin and Venereal Diseases, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Genovefa Chronopoulou (G)

Biopathology Department, Athens Medical Center, 5-7 Distomou Str., 15125 Marousi, Greece.

Nikos Pantazis (N)

Department of Hygiene, Epidemiology and Medical Statistics, Faculty of Medicine, School of Health Sciences, National and Kapodistrian University of Athens, 75 Mikras Asias Str., 11527 Athens, Greece.

Maria Kantzanou (M)

Department of Microbiology, School of Medicine, National and Kapodistrian University of Athens, 75 Mikras Asias Str., 11527 Athens, Greece.

Helena C Maltezou (HC)

Directorate of Research, Studies and Documentation, National Public Health Organization, 3-5 Agrafon Str., 15123 Athens, Greece.

Athanasios Tsakris (A)

Department of Microbiology, School of Medicine, National and Kapodistrian University of Athens, 75 Mikras Asias Str., 11527 Athens, Greece.

Classifications MeSH