Oncogeriatric Developments.

Acute myeloid leukemia Breast cancer Colon cancer Comprehensive geriatric assessment Esophageal cancer Geriatric oncology Pancreatic cancer Prostate cancer Public policy

Journal

Gerontology
ISSN: 1423-0003
Titre abrégé: Gerontology
Pays: Switzerland
ID NLM: 7601655

Informations de publication

Date de publication:
2023
Historique:
received: 02 01 2023
accepted: 30 05 2023
medline: 14 9 2023
pubmed: 16 6 2023
entrez: 15 6 2023
Statut: ppublish

Résumé

Cancer is a disease of aging and is rapidly becoming the number one cause of mortality in older people. Over their lifetime, one in two men and one in three women will develop a cancer, with half of the risk being beyond the age of seventy. Therefore, cancer is a problem frequently encountered by geriatricians. In this article, we review a few recent progresses that will be of interest to the geriatric community. First, we now have robust evidence that a comprehensive geriatric assessment and management change outcomes in older cancer patients, notably allowing decreased treatment toxicity, better treatment completion, and increased functional outcomes. In gastrointestinal cancers and breast cancer, several recent studies have addressed when treatment intensity can be decreased, and when it cannot. New treatments for acute myeloid leukemia are finally beginning to improve outcomes for older patients and such patients should be referred to oncologists for management. In prostate cancer, new imaging techniques (e.g., PSMA scan) and treatment options can allow better treatment targeting and spare some hormonal and chemotherapy toxicity. Finally, we review recent public policy efforts to address the epidemiologic wave of cancer in older patients on a global scale.

Identifiants

pubmed: 37321185
pii: 000531559
doi: 10.1159/000531559
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1045-1055

Informations de copyright

© 2023 S. Karger AG, Basel.

Auteurs

Martine Extermann (M)

Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, Florida, USA.

Mohammed Al-Jumayli (M)

Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, Florida, USA.

Christine Sam (C)

Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, Florida, USA.

Julie A Kish (JA)

Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, Florida, USA.

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Classifications MeSH