Respiratory Center Function and Its Impact in Obesity Hypoventilation Syndrome Treatment.
Non-invasive ventilation
Obesity-hypoventilation syndrome
Respiratory center
Sleep apnea
Journal
Archivos de bronconeumologia
ISSN: 1579-2129
Titre abrégé: Arch Bronconeumol
Pays: Spain
ID NLM: 0354720
Informations de publication
Date de publication:
Aug 2023
Aug 2023
Historique:
received:
06
04
2023
revised:
23
05
2023
accepted:
24
05
2023
medline:
4
8
2023
pubmed:
16
6
2023
entrez:
15
6
2023
Statut:
ppublish
Résumé
Patients with obesity hypoventilation syndrome (OHS) need treatment with positive pressure either with continuous (CPAP) or double pressure (NIV). The apnea-hypopnea index (AHI) is considered a key data for making therapeutic decisions. We hypothesized that HR may be an useful tool to establish different phenotypes and individualize treatment in patients with OHS. Our objective was to analyze the role of the respiratory center response to hypercapnia (HR) in the adequacy of positive airway pressure therapy. We included subjects with OHS treated with CPAP or NIV according to AHI and baseline pCO 67 subjects were included of 68(11) years old, 37 (55%) males, initially 45 (67%) treated with NIV and 22 (33%) with CPAP, one case was excluded and in 25 (38%) the treatment was changed. Finally, CPAP was adequate for 29 subjects (44%) and NIV for 37 (56%). The CPAP group showed AHI 57/h (24) and p0.1/pEtCO Measuring the RH of the respiratory center helps to select the most appropriate treatment for patients with OHS.
Identifiants
pubmed: 37321904
pii: S0300-2896(23)00171-0
doi: 10.1016/j.arbres.2023.05.013
pii:
doi:
Types de publication
Journal Article
Langues
eng
spa
Sous-ensembles de citation
IM
Pagination
497-501Informations de copyright
Copyright © 2023 SEPAR. Published by Elsevier España, S.L.U. All rights reserved.