The intersection of undernutrition, microbiome, and child development in the first years of life.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
15 06 2023
15 06 2023
Historique:
received:
04
04
2023
accepted:
05
06
2023
medline:
19
6
2023
pubmed:
16
6
2023
entrez:
15
6
2023
Statut:
epublish
Résumé
Undernutrition affects about one out of five children worldwide. It is associated with impaired growth, neurodevelopment deficits, and increased infectious morbidity and mortality. Undernutrition, however, cannot be solely attributed to a lack of food or nutrient deficiency but rather results from a complex mix of biological and environmental factors. Recent research has shown that the gut microbiome is intimately involved in the metabolism of dietary components, in growth, in the training of the immune system, and in healthy development. In this review, we look at these features in the first three years of life, which is a critical window for both microbiome establishment and maturation and child development. We also discuss the potential of the microbiome in undernutrition interventions, which could increase efficacy and improve child health outcomes.
Identifiants
pubmed: 37322020
doi: 10.1038/s41467-023-39285-9
pii: 10.1038/s41467-023-39285-9
pmc: PMC10272168
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3554Informations de copyright
© 2023. The Author(s).
Références
Lancet Glob Health. 2018 Mar;6(3):e316-e329
pubmed: 29396219
Cell. 2018 Sep 20;175(1):146-158.e15
pubmed: 30100182
Nat Rev Microbiol. 2011 Apr;9(4):279-90
pubmed: 21407244
Cell. 2016 Feb 25;164(5):859-71
pubmed: 26898329
J Pediatr. 2013 Aug;163(2):416-23
pubmed: 23452586
Nature. 2014 Jun 19;510(7505):417-21
pubmed: 24896187
J Nutr. 2019 Jun 1;149(6):1075-1088
pubmed: 31006815
Science. 2016 Jun 24;352(6293):1533
pubmed: 27339978
Cell Host Microbe. 2018 Jul 11;24(1):133-145.e5
pubmed: 30001516
Nature. 2023 Jan;613(7945):639-649
pubmed: 36697862
Am J Clin Nutr. 2010 Dec;92(6):1406-15
pubmed: 20962160
Curr Dev Nutr. 2019 Jan 15;3(3):nzz005
pubmed: 30891538
Sci Rep. 2019 Aug 28;9(1):12476
pubmed: 31462648
Science. 2013 Feb 1;339(6119):548-54
pubmed: 23363771
Sci Rep. 2021 Mar 8;11(1):5426
pubmed: 33686095
Cells. 2022 Jul 23;11(15):
pubmed: 35892575
J Trop Pediatr. 2022 Feb 3;68(2):
pubmed: 35149871
Lancet. 2007 Mar 3;369(9563):740
pubmed: 17336646
N Engl J Med. 2020 Jul 23;383(4):321-333
pubmed: 32706533
Front Immunol. 2022 Mar 23;13:816282
pubmed: 35401569
Gut. 2017 Nov;66(11):1956-1967
pubmed: 28774885
Am J Trop Med Hyg. 2022 Dec 12;108(1):206-211
pubmed: 36509053
Neuropharmacology. 2023 Apr 1;227:109453
pubmed: 36738776
Cell Host Microbe. 2015 May 13;17(5):690-703
pubmed: 25974306
Trends Microbiol. 2019 Feb;27(2):131-147
pubmed: 30529020
JCI Insight. 2020 Nov 5;5(21):
pubmed: 33001863
Genome Med. 2020 Oct 27;12(1):92
pubmed: 33109272
Science. 2016 Feb 19;351(6275):
pubmed: 26912898
Science. 2020 Feb 28;367(6481):
pubmed: 32108090
Science. 2019 Sep 6;365(6457):984-985
pubmed: 31488675
Gut. 2019 Apr;68(4):645-653
pubmed: 30448776
Nat Microbiol. 2021 Apr;6(4):445-454
pubmed: 33589804
Nat Commun. 2023 Feb 14;14(1):654
pubmed: 36788215
Front Microbiol. 2011 Nov 21;2:228
pubmed: 22125551
Autoimmun Rev. 2016 Sep;15(9):859-69
pubmed: 27392501
Cell Host Microbe. 2018 Jul 11;24(1):146-154.e4
pubmed: 30001517
J Health Popul Nutr. 2015 May 02;34:8
pubmed: 26825706
Cell Rep Med. 2020 Dec 22;1(9):100156
pubmed: 33377127
EBioMedicine. 2021 Jun;68:103421
pubmed: 34139432
Ann Nutr Metab. 2012;61 Suppl 1:8-17
pubmed: 23343943
Lancet Glob Health. 2018 Mar;6(3):e302-e315
pubmed: 29396217
Nature. 2012 May 09;486(7402):222-7
pubmed: 22699611
Matern Child Nutr. 2020 Jan;16(1):e12898
pubmed: 31667981
Mol Cell. 2016 Dec 1;64(5):982-992
pubmed: 27889451
Nature. 2018 Oct;562(7728):583-588
pubmed: 30356187
Science. 2016 Apr 29;352(6285):565-9
pubmed: 27126040
Nat Med. 2016 Oct 06;22(10):1079-1089
pubmed: 27711063
Sci Rep. 2019 Jun 24;9(1):9084
pubmed: 31235833
Nutrients. 2019 Oct 29;11(11):
pubmed: 31671757
Sci Transl Med. 2016 Nov 23;8(366):366ra164
pubmed: 27881825
J Biol Chem. 2020 Mar 20;295(12):4035-4048
pubmed: 32014993
Nat Rev Microbiol. 2021 Jan;19(1):55-71
pubmed: 32887946
Nutrients. 2021 May 06;13(5):
pubmed: 34066577
Science. 2022 Jun 10;376(6598):1220-1223
pubmed: 35679413
Trends Microbiol. 2019 Oct;27(10):824-835
pubmed: 31178123
Nature. 2020 Oct;586(7828):281-286
pubmed: 32968276
Nat Commun. 2021 Nov 25;12(1):6860
pubmed: 34824233
Nat Microbiol. 2020 Jun;5(6):838-847
pubmed: 32284564
Sci Rep. 2020 Dec 16;10(1):22092
pubmed: 33328537
Science. 2019 Jul 12;365(6449):
pubmed: 31296738
Cell Rep Med. 2021 May 18;2(5):100280
pubmed: 34095882
Sci Transl Med. 2015 Feb 25;7(276):276ra24
pubmed: 25717097
Science. 2019 Jul 12;365(6449):
pubmed: 31296739
Nat Commun. 2020 Mar 24;11(1):1452
pubmed: 32210229
Sci Transl Med. 2016 Jun 15;8(343):343ra81
pubmed: 27306663
Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2209589119
pubmed: 36197997
Nutrients. 2019 Jun 19;11(6):
pubmed: 31248104
Sci Transl Med. 2022 Apr 13;14(640):eabk1107
pubmed: 35417188
BMJ. 2014 Apr 15;348:g2267
pubmed: 24735883
J Pediatr. 2018 Dec;203:47-54.e4
pubmed: 30173873
N Engl J Med. 2021 Apr 22;384(16):1517-1528
pubmed: 33826814
Gut. 2015 May;64(5):731-42
pubmed: 25143342
Front Cell Infect Microbiol. 2019 Apr 02;9:85
pubmed: 31001489
Nat Commun. 2021 Jan 26;12(1):443
pubmed: 33500411
Sci Rep. 2022 Jun 8;12(1):9456
pubmed: 35676397
EBioMedicine. 2021 Jun;68:103400
pubmed: 34098340
Cell Host Microbe. 2021 May 12;29(5):765-776.e3
pubmed: 33794185
Nat Commun. 2018 Oct 26;9(1):4462
pubmed: 30367045
Nat Rev Gastroenterol Hepatol. 2017 May;14(5):315-320
pubmed: 28356581
J Pediatr Gastroenterol Nutr. 2016 Sep;63(3):379-85
pubmed: 27548249
Sci Rep. 2016 May 17;6:26051
pubmed: 27183876
Sci Rep. 2023 Feb 1;13(1):1845
pubmed: 36725893
Nutrients. 2017 Jul 19;9(7):
pubmed: 28753958
Cell Host Microbe. 2020 Feb 12;27(2):199-212.e5
pubmed: 32053789
Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8489-E8498
pubmed: 30126990
EBioMedicine. 2021 Nov;73:103644
pubmed: 34695658
BMC Public Health. 2020 Feb 17;20(1):242
pubmed: 32066412
Nature. 2018 Mar 8;555(7695):210-215
pubmed: 29489753