Bilateral anterior uveitis as a presenting feature of Juvenile Xanthogranuloma in a neonate.


Journal

American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 29 12 2022
revised: 14 05 2023
accepted: 27 05 2023
medline: 16 6 2023
pubmed: 16 6 2023
entrez: 16 6 2023
Statut: epublish

Résumé

To report a case of diffuse xanthogranuloma presenting as bilateral anterior uveitis in a neonate. A neonate was brought by the parents with complaints of redness, watering, and photophobia in both eyes for 10 days. Examination under anesthesia revealed the presence of bilateral hyphema, fibrinous membrane, corneal haze, and raised intraocular pressure (IOP). Ultrasound Biomicroscopy revealed diffuse bilateral iris thickening. The child was managed medically with topical glaucoma medications, topical steroids, and cycloplegics. The child responded well with the resolution of hyphema, anterior chamber inflammation, and reduction of IOP. In neonates and infants presenting with bilateral uveitis, spontaneous hyphema, and secondary glaucoma, even in the absence of a well-defined iris lesion, diffuse juvenile xanthogranuloma should be considered as a differential diagnosis.

Identifiants

pubmed: 37323587
doi: 10.1016/j.ajoc.2023.101867
pii: S2451-9936(23)00075-0
pmc: PMC10265478
doi:

Types de publication

Case Reports

Langues

eng

Pagination

101867

Informations de copyright

© 2023 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Références

Pediatr Blood Cancer. 2023 Apr;70(4):e30104
pubmed: 36519556
Br J Ophthalmol. 1999 Mar;83(3):375-6
pubmed: 10365052
J Glaucoma. 2016 Aug;25(8):e759-60
pubmed: 27483333
Br J Ophthalmol. 2002 Mar;86(3):352-3
pubmed: 11864899
Asia Pac J Ophthalmol (Phila). 2019 Jan-Feb;8(1):30-35
pubmed: 30375203
Surv Ophthalmol. 2022 Mar-Apr;67(2):510-529
pubmed: 34181974
F1000Prime Rep. 2014 Jun 02;6:41
pubmed: 24991418
J Pediatr Ophthalmol Strabismus. 2004 Jan-Feb;41(1):18-24
pubmed: 14974830
Open Ophthalmol J. 2016 Feb 29;10:27-32
pubmed: 27014384
Genet Med. 2021 Aug;23(8):1506-1513
pubmed: 34012067
Am J Ophthalmol. 1965 Dec;60(6):1011-35
pubmed: 4955207
Case Rep Ophthalmol. 2020 Dec 21;11(3):668-675
pubmed: 33568985
Arch Ophthalmol. 1998 Mar;116(3):377-9
pubmed: 9514494
Actas Dermosifiliogr (Engl Ed). 2020 Nov;111(9):725-733
pubmed: 32721389
Arch Dermatol. 1995 Aug;131(8):904-8
pubmed: 7632061
Pediatr Dermatol. 2020 Jul;37(4):637-644
pubmed: 32468628
Ophthalmology. 2015 Oct;122(10):2130-8
pubmed: 26189188
J Am Acad Dermatol. 2017 Jun;76(6):1084-1087
pubmed: 28189268
Surv Ophthalmol. 1994 Jul-Aug;39(1):65-71
pubmed: 7974193

Auteurs

Brajesh Lahri (B)

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Zakir Hussain (Z)

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Neerja Gupta (N)

Department of Paediatrics, Genetics Division, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Shikha Gupta (S)

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Abhishek Singh (A)

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Viney Gupta (V)

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Classifications MeSH