SARS-CoV-2 Vaccination IgG Antibody Responses in Patients with Hematologic Malignancies in a Myeloid Enriched Cohort: A Single Center Observation.
Antibody Response
Hematologic Malignancy
SARS-CoV-2 Vaccination
Journal
Acta medica academica
ISSN: 1840-2879
Titre abrégé: Acta Med Acad
Pays: Bosnia and Herzegovina
ID NLM: 101587903
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
04
02
2023
accepted:
13
04
2023
medline:
19
6
2023
pubmed:
16
6
2023
entrez:
16
6
2023
Statut:
ppublish
Résumé
Patients diagnosed with hematologic malignancies are at increased risk for severe SARS-CoV-2 infection. We evaluated the serological IgG response following two doses of the SARS-CoV-2 vaccine in patients with hematologic malignancies. Patients treated at UT Southwestern Medical Center with a diagnosis of a myeloid or lymphoid neoplasm were included. SARS-CoV-2 vaccination response was defined as a positive quantifiable spike IgG antibody titer. Sixty patients were included in the study and 60% were diagnosed with a myeloid neoplasm. The majority (85%) of the patients with a myeloid malignancy and 50% of the patients with a lymphoid malignancy mounted a serological response after receiving two doses of the vaccine. Vaccination should be offered irrespective of ongoing treatment or active disease. Findings require validation in a larger cohort of patients.
Identifiants
pubmed: 37326395
pii: ama2006-124.399
doi: 10.5644/ama2006-124.399
pmc: PMC10316070
doi:
Substances chimiques
COVID-19 Vaccines
0
Immunoglobulin G
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
30-36Informations de copyright
Copyright © Hoff et al. This article is available under a Creative Commons License (Attribution 4.0 International).
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