Pharmacogenetic testing in psychiatry: Perspective on clinical utility.

Humans Pharmacogenomic Testing Pharmacogenetics Psychiatry
Pharmacogenomics Precision medicine Psychiatry PGx

Journal

Asian journal of psychiatry
ISSN: 1876-2026
Titre abrégé: Asian J Psychiatr
Pays: Netherlands
ID NLM: 101517820

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 13 04 2023
revised: 07 06 2023
accepted: 09 06 2023
medline: 31 7 2023
pubmed: 17 6 2023
entrez: 16 6 2023
Statut: ppublish

Résumé

Pharmacogenetic studies the influence of inherited characteristics on medication. While different from pharmacogenomics, which is a study of the entire genome in relation to medication effect, their distinction remains inconsistent, and the two terms are used interchangeably. Although the potential of pharmacogenomics in psychiatry is apparent and its clinical utility is suboptimal, the uptake of recommendations and guidelines is minimal and research into PGx is not diverse. This article offers an overview of pharmacogenetics (PGx) in psychiatry, explores the difficulties, and provides recommendations on improving its applicability and clinical utility.

Identifiants

DOI: 10.1016/j.ajp.2023.103674 PMID: 37327563
pubmed: 37327563
pii: S1876-2018(23)00230-7
doi: 10.1016/j.ajp.2023.103674
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

103674

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest All authors declare no interest.

Auteurs

Frances Adiukwu (F)

Department of Mental Health, University of Port Harcourt, Rivers State, Nigeria. Electronic address: frances.adiukwu@uniport.edu.ng.

Olufisayo Adesokun (O)

Department of Neuropsychiatry, University of Port Harcourt Teaching Hospital, Rivers State, Nigeria. Electronic address: adesaayo@gmail.com.

Emmanuel Essien (E)

Department of Psychiatry, University of Calabar, Calabar, Nigeria. Electronic address: mannyessien@gmail.com.

Nadir Yalcin (N)

Department of Clinical Pharmacology, Faculty of Pharmacy, Hacettepe University, Ankara 06100, Turkey. Electronic address: nadir.yalcin@hacettepe.edu.tr.

Ramdas Ransing (R)

Department of Psychiatry, Clinical Neurosciences and Addiction Medicine, All India Institute of Medical Sciences, Guwahati, Assam 781101, India. Electronic address: ramdas_ransing123@yahoo.co.in.

Sachin Nagendrappa (S)

St Johns Medical College Hospital, Bangaluru 34, India. Electronic address: sachin.n@stjohns.in.

Chonnakarn Jatchavala (C)

Department of Psychiatry, Faculty of Medicine, Prince Songkhla University, Songkhla 90110, Thailand. Electronic address: jchonnak@gmail.com.

Ayotunde Bolatito Olakunke (AB)

Child and Adolescent Psychiatry Unit, Department of Behavioural Sciences, University of Ilorin/ University of Ilorin Teaching Hospital, Ilorin, Nigeria.

Faisal A Nawaz (FA)

Department of Psychiatry, Al Amal Psychiatric Hospital, Dubai, United Arab Emirates. Electronic address: faisal.nawaz@ehs.gov.ae.

Nagina Khan (N)

CHiMES Collaborative, Department of Psychiatry, University of Oxford, Warneford Hospital, Headington, Oxford OX3 7JX, UK. Electronic address: nagina.khan@psych.ox.ac.uk.

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