Neuropsychological outcomes after epilepsy surgery: A comparison of stereo electroencephalography and subdural electrodes.
drug-resistant epilepsy
functional brain mapping
intracranial electroencephalography
language mapping
Journal
European journal of neurology
ISSN: 1468-1331
Titre abrégé: Eur J Neurol
Pays: England
ID NLM: 9506311
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
revised:
06
06
2023
received:
22
01
2023
accepted:
12
06
2023
pmc-release:
01
10
2024
medline:
8
9
2023
pubmed:
17
6
2023
entrez:
17
6
2023
Statut:
ppublish
Résumé
We analyzed the association of neuropsychological outcomes after epilepsy surgery with the intracranial electrode type (stereo electroencephalography [SEEG] and subdural electrodes [SDE]), and electrical stimulation mapping (ESM) of speech/language. Drug-resistant epilepsy patients who underwent comprehensive neuropsychological evaluation before and 1 year after epilepsy surgery were included. SEEG and SDE subgroups were matched by age, handedness, operated hemisphere, and seizure freedom. Postsurgical neuropsychological outcomes (adjusted for presurgical scores) and reliable change indices were analyzed as functions of electrode type and ESM. Ninety-nine patients aged 6-29 years were included with similar surgical resection/ablation volumes in the SEEG and SDE subgroups. Most of the neuropsychological outcomes were comparable between SEEG and SDE subgroups; however, Working Memory and Processing Speed were significantly improved in the SEEG subgroup. Undergoing language ESM was associated with significant improvements in Spelling, Letter-Word Identification, Vocabulary, Verbal Comprehension, Verbal Learning, and Story Memory scores, but a decline in Calculation scores. Intracranial evaluations with SEEG and SDE are comparable in terms of long-term postsurgical neuropsychological outcomes. Our data suggest that SEEG may be associated with improvements in working memory and processing speed, representing cognitive domains served by spatially distributed networks. Our study also supports wider use of language ESM before epilepsy surgery, preferably using other language tasks in addition to visual naming. Rather than the type of electrode, postsurgical neuropsychological outcomes are driven by whether language ESM was performed or not, with beneficial effects of language mapping.
Sections du résumé
BACKGROUND AND PURPOSE
We analyzed the association of neuropsychological outcomes after epilepsy surgery with the intracranial electrode type (stereo electroencephalography [SEEG] and subdural electrodes [SDE]), and electrical stimulation mapping (ESM) of speech/language.
METHODS
Drug-resistant epilepsy patients who underwent comprehensive neuropsychological evaluation before and 1 year after epilepsy surgery were included. SEEG and SDE subgroups were matched by age, handedness, operated hemisphere, and seizure freedom. Postsurgical neuropsychological outcomes (adjusted for presurgical scores) and reliable change indices were analyzed as functions of electrode type and ESM.
RESULTS
Ninety-nine patients aged 6-29 years were included with similar surgical resection/ablation volumes in the SEEG and SDE subgroups. Most of the neuropsychological outcomes were comparable between SEEG and SDE subgroups; however, Working Memory and Processing Speed were significantly improved in the SEEG subgroup. Undergoing language ESM was associated with significant improvements in Spelling, Letter-Word Identification, Vocabulary, Verbal Comprehension, Verbal Learning, and Story Memory scores, but a decline in Calculation scores.
CONCLUSIONS
Intracranial evaluations with SEEG and SDE are comparable in terms of long-term postsurgical neuropsychological outcomes. Our data suggest that SEEG may be associated with improvements in working memory and processing speed, representing cognitive domains served by spatially distributed networks. Our study also supports wider use of language ESM before epilepsy surgery, preferably using other language tasks in addition to visual naming. Rather than the type of electrode, postsurgical neuropsychological outcomes are driven by whether language ESM was performed or not, with beneficial effects of language mapping.
Identifiants
pubmed: 37329329
doi: 10.1111/ene.15929
pmc: PMC10529267
mid: NIHMS1912869
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
2986-2998Subventions
Organisme : NINDS NIH HHS
ID : R01 NS115929
Pays : United States
Informations de copyright
© 2023 European Academy of Neurology.
Références
Clin Neurophysiol. 2017 Oct;128(10):2087-2093
pubmed: 28774583
Neurosurg Clin N Am. 2016 Jan;27(1):83-95
pubmed: 26615111
Epilepsia. 2009 Oct;50(10):2267-75
pubmed: 19624716
Epilepsia. 2014 Apr;55(4):507-18
pubmed: 24512473
JAMA Neurol. 2019 Jun 1;76(6):672-681
pubmed: 30830149
J Clin Neurophysiol. 2016 Dec;33(6):478-482
pubmed: 26840984
Neuroimage. 2010 Jan 15;49(2):1190-9
pubmed: 19796691
Clin Neurophysiol. 2020 Dec;131(12):2851-2860
pubmed: 33137575
Clin Neurophysiol. 2021 Dec;132(12):2948-2958
pubmed: 34715419
J Neurosurg. 2021 Feb 26;:1-11
pubmed: 33636700
Epilepsy Behav. 2012 Jun;24(2):194-8
pubmed: 22569529
Trends Cogn Sci. 2005 Nov;9(11):512-8
pubmed: 16214387
J Clin Neurophysiol. 1992 Apr;9(2):288-93
pubmed: 1592899
Epilepsy Res. 2019 Mar;151:17-23
pubmed: 30721879
Neuropsychol Rev. 2007 Dec;17(4):477-89
pubmed: 18004662
Epilepsia. 2007 Mar;48(3):531-8
pubmed: 17326797
Brain. 2017 May 1;140(5):1351-1370
pubmed: 28334963
Epilepsy Behav. 2019 Oct;99:106395
pubmed: 31422309
Neurology. 2001 Jan 9;56(1):56-61
pubmed: 11148236
Epilepsia. 2016 Mar;57(3):386-401
pubmed: 26899389
Clin Neurophysiol. 2017 Oct;128(10):2078-2086
pubmed: 28778475
Clin Neurophysiol. 2020 Aug;131(8):1691-1701
pubmed: 32504928
J Neurosurg. 2014 Nov;121(5):1239-46
pubmed: 25148007
Epilepsy Behav. 2018 Jul;84:148-151
pubmed: 29803145
Epilepsia. 2013 May;54(5):828-39
pubmed: 23294329
Neuroscience. 2006 Apr 28;139(1):51-8
pubmed: 16352402
Stat Sci. 2010 Feb 1;25(1):1-21
pubmed: 20871802
Brain Stimul. 2021 Sep-Oct;14(5):1184-1196
pubmed: 34358704
Neuropsychology. 1999 Jan;13(1):3-9
pubmed: 10067770
Epilepsy Res. 2021 Dec 20;179:106845
pubmed: 34968894
Neuroscientist. 2007 Jun;13(3):257-67
pubmed: 17519368
Epilepsia. 2011 May;52(5):857-69
pubmed: 21426331
J Clin Neurophysiol. 2016 Dec;33(6):511-521
pubmed: 27918346
Seizure. 2020 Aug;80:183-191
pubmed: 32604001
Epilepsia. 2010 Feb;51(2):206-13
pubmed: 19694793
Stroke. 2009 Mar;40(3):677-82
pubmed: 19131654
Brain Lang. 2017 Dec;175:71-76
pubmed: 29024845
J Neurosurg. 2020 Apr 24;134(3):1251-1261
pubmed: 32330883
J Clin Neurophysiol. 2022 Sep 1;39(6):474-480
pubmed: 33181594
Front Neurol. 2021 Apr 27;12:669406
pubmed: 33986721
Neuroimage Clin. 2014 May 21;4:828-37
pubmed: 24936433
Neurology. 2010 Dec 14;75(24):2221-8
pubmed: 21172845