Central Nervous System Vasculitis: Primary Angiitis of the Central Nervous System and Central Nervous System Manifestations of Systemic Vasculitis.


Journal

Rheumatic diseases clinics of North America
ISSN: 1558-3163
Titre abrégé: Rheum Dis Clin North Am
Pays: United States
ID NLM: 8708093

Informations de publication

Date de publication:
08 2023
Historique:
medline: 20 6 2023
pubmed: 19 6 2023
entrez: 18 6 2023
Statut: ppublish

Résumé

Central nervous system vasculitis (CNSV) is a group of disorders leading to inflammatory vasculopathy within the brain, spinal cord, and leptomeninges. CNSV is divided into primary angiitis of the central nervous system (PACNS) and secondary CNSV based on the underlying etiology. PACNS is a rare inflammatory disorder with poorly understood pathophysiology and heterogeneous and highly variable clinical features. The diagnosis depends on a combination of clinical and laboratory variables, multimodal imaging, and histopathological examination as well as exclusion of mimics. Several systemic vasculitides, infectious etiologies and connective tissue disorders have been shown to cause secondary CNSV and require prompt recognition.

Identifiants

pubmed: 37331735
pii: S0889-857X(23)00042-X
doi: 10.1016/j.rdc.2023.03.011
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

603-616

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Moein Amin (M)

Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.

Ken Uchino (K)

Cerebrovascular Center, Cleveland Clinic, Cleveland, OH, USA.

Rula A Hajj-Ali (RA)

Cleveland Clinic Center for Vasculitis Care and Research, Cleveland Clinic, 9500 Euclid Avenue, A50, Cleveland, OH 44195, USA. Electronic address: HAJJALR@ccf.org.

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Classifications MeSH