The Future of Vasculitis: A Manifesto.
ANCA-associated vasculitis
Biomarkers
Clinical trials
Giant cell arteritis
Takayasu arteritis
Vasculitis
Journal
Rheumatic diseases clinics of North America
ISSN: 1558-3163
Titre abrégé: Rheum Dis Clin North Am
Pays: United States
ID NLM: 8708093
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
medline:
20
6
2023
pubmed:
19
6
2023
entrez:
18
6
2023
Statut:
ppublish
Résumé
Predictions for a general path forward in vasculitis care and research are provided based on advances made in the past 20 years. Prospects for advances in translational research with potential to improve care are highlighted, including identification of hemato-inflammatory diseases, autoantigens, disease mechanisms in animal models, and biomarkers. A list of active randomized trials is provided, and areas of potential paradigm shifts in care are highlighted. The importance of patient involvement and international collaboration is noted, and a plea is made for innovative trial designs that would improve access of patients to trials and to clinical experts at referral centers.
Identifiants
pubmed: 37331742
pii: S0889-857X(23)00045-5
doi: 10.1016/j.rdc.2023.03.014
pii:
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
713-729Informations de copyright
Published by Elsevier Inc.