Axonal mapping of the motor cranial nerves.
facial muscles
facial nerve
hypoglossal nerve
masseteric nerve
motor control
proprioception
sensory feedback
sympathetic axons
Journal
Frontiers in neuroanatomy
ISSN: 1662-5129
Titre abrégé: Front Neuroanat
Pays: Switzerland
ID NLM: 101477943
Informations de publication
Date de publication:
2023
2023
Historique:
received:
31
03
2023
accepted:
12
05
2023
medline:
19
6
2023
pubmed:
19
6
2023
entrez:
19
6
2023
Statut:
epublish
Résumé
Basic behaviors, such as swallowing, speech, and emotional expressions are the result of a highly coordinated interplay between multiple muscles of the head. Control mechanisms of such highly tuned movements remain poorly understood. Here, we investigated the neural components responsible for motor control of the facial, masticatory, and tongue muscles in humans using specific molecular markers (ChAT, MBP, NF, TH). Our findings showed that a higher number of motor axonal population is responsible for facial expressions and tongue movements, compared to muscles in the upper extremity. Sensory axons appear to be responsible for neural feedback from cutaneous mechanoreceptors to control the movement of facial muscles and the tongue. The newly discovered sympathetic axonal population in the facial nerve is hypothesized to be responsible for involuntary control of the muscle tone. These findings shed light on the pivotal role of high efferent input and rich somatosensory feedback in neuromuscular control of finely adjusted cranial systems.
Identifiants
pubmed: 37332322
doi: 10.3389/fnana.2023.1198042
pmc: PMC10272770
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1198042Informations de copyright
Copyright © 2023 Tereshenko, Maierhofer, Dotzauer, Laengle, Politikou, Carrero Rojas, Festin, Luft, Jaklin, Hruby, Gohritz, Farina, Blumer, Bergmeister and Aszmann.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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