Effects of frankincense on experimentally induced renal stones in rats.

Boswellia Luban frankincense kidney rats renal stones

Journal

BJUI compass
ISSN: 2688-4526
Titre abrégé: BJUI Compass
Pays: United States
ID NLM: 101764975

Informations de publication

Date de publication:
Jul 2023
Historique:
received: 12 11 2022
revised: 02 01 2023
accepted: 16 01 2023
medline: 19 6 2023
pubmed: 19 6 2023
entrez: 19 6 2023
Statut: epublish

Résumé

Frankincense (Luban) is a resin obtained from trees of genus A rat model of urolithiasis induced by The lithogenic effects of HLP, such as an increase in urine oxalate and cystine, an increase in plasma uric acid and an increase in kidney levels of calcium and oxalate, have all been best significantly reversed by the Luban dose of 150 mg/kg/day. The histological changes of HLP on the kidney tissue including calcium oxalate crystal formation, cystic dilatation, high degree of tubular necrosis, inflammatory changes, atrophy and fibrosis have also been ameliorated by Luban dose of 150 mg/kg/day. Luban has shown a significant improvement in the treatment and prevention of experimentally induced renal stones, particularly at a dose of 150 mg/kg/day. Further studies on the effect of Luban in other animal models and humans with urolithiasis are warranted.

Identifiants

pubmed: 37334022
doi: 10.1002/bco2.227
pii: BCO2227
pmc: PMC10268574
doi:

Types de publication

Journal Article

Langues

eng

Pagination

437-445

Informations de copyright

© 2023 The Authors. BJUI Compass published by John Wiley & Sons Ltd on behalf of BJU International Company.

Déclaration de conflit d'intérêts

All authors report no conflict of interest.

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Auteurs

Mohamed S Al-Marhoon (MS)

Urology Division, Department of Surgery, College of Medicine and Health Sciences Sultan Qaboos University Seeb Sultanate of Oman.

Ahmed Al-Harrasi (A)

Natural and Medical Sciences Research Center University of Nizwa Nizwa Sultanate of Oman.

Khurram Siddiqui (K)

Urology Division, Department of Surgery, College of Medicine and Health Sciences Sultan Qaboos University Seeb Sultanate of Oman.

Mohammed Ashique (M)

Department of Pharmacology and Clinical Pharmacy, College of Medicine and Health Sciences Sultan Qaboos University Seeb Sultanate of Oman.

Haytham Ali (H)

Department of Animal and Veterinary Sciences, College of Agricultural and Marine Sciences Sultan Qaboos University Seeb Sultanate of Oman.

Badreldin H Ali (BH)

Department of Pharmacology and Clinical Pharmacy, College of Medicine and Health Sciences Sultan Qaboos University Seeb Sultanate of Oman.

Classifications MeSH