Microfluidics based bioimaging with cost-efficient fabrication of multi-level micrometer-sized trenches.
Journal
Biomicrofluidics
ISSN: 1932-1058
Titre abrégé: Biomicrofluidics
Pays: United States
ID NLM: 101293825
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
received:
25
03
2023
accepted:
31
05
2023
pmc-release:
15
06
2024
medline:
19
6
2023
pubmed:
19
6
2023
entrez:
19
6
2023
Statut:
epublish
Résumé
Microfluidic devices, through their vast applicability as tools for miniaturized experimental setups, have become indispensable for cutting edge research and diagnostics. However, the high operational cost and the requirement of sophisticated equipment and clean room facility for the fabrication of these devices make their use unfeasible for many research laboratories in resource limited settings. Therefore, with the aim of increasing accessibility, in this article, we report a novel, cost-effective micro-fabrication technique for fabricating multi-layer microfluidic devices using only common wet-lab facilities, thereby significantly lowering the cost. Our proposed process-flow-design eliminates the need for a mastermold, does not require any sophisticated lithography tools, and can be executed successfully outside a clean room. In this work, we also optimized the critical steps (such as spin coating and wet etching) of our fabrication process and validated the process flow and the device by trapping and imaging
Identifiants
pubmed: 37334275
doi: 10.1063/5.0151868
pii: 5.0151868
pmc: PMC10275646
doi:
Types de publication
Journal Article
Langues
eng
Pagination
034103Informations de copyright
© 2023 Author(s).
Déclaration de conflit d'intérêts
The authors have no conflicts to disclose.
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