The significance of immunonutrition nutritional support in patients undergoing postoperative adjuvant chemotherapy for lung cancer: case-control study.
Adjuvant chemotherapy
Lung cancer
Nutrition
Resection
Journal
World journal of surgical oncology
ISSN: 1477-7819
Titre abrégé: World J Surg Oncol
Pays: England
ID NLM: 101170544
Informations de publication
Date de publication:
19 Jun 2023
19 Jun 2023
Historique:
received:
13
02
2023
accepted:
14
06
2023
medline:
21
6
2023
pubmed:
20
6
2023
entrez:
19
6
2023
Statut:
epublish
Résumé
In this study, the effect of postoperative early nutritional supplementation on the course of the disease was investigated in patients who were operated for non-small cell lung cancer and received adjuvant chemotherapy. The study examined the data of patients who anatomical pulmonary resection for non-small cell lung cancer and who were treated with adjuvant chemotherapy at our clinic between January 2014 and January 2020. Patients who received early postoperative nutritional supplements and those who continued with a normal diet were compared in terms of complications, mortality, recurrence, and survival. The study sample consisted of 68 (84%) male and 13 (16%) female patients, and the mean duration of postoperative follow-up was 31.6 ± 17.9 (4-75) months. Metastasis was identified in eight (17.4%) patients in Grup Early nutritional supplements should be considered as having a positive effect especially on survival in this specific patient group involving factors with high catabolic effects, such as neoplasia, operation, and chemotherapy together.
Sections du résumé
BACKGROUND
BACKGROUND
In this study, the effect of postoperative early nutritional supplementation on the course of the disease was investigated in patients who were operated for non-small cell lung cancer and received adjuvant chemotherapy.
METHODS
METHODS
The study examined the data of patients who anatomical pulmonary resection for non-small cell lung cancer and who were treated with adjuvant chemotherapy at our clinic between January 2014 and January 2020. Patients who received early postoperative nutritional supplements and those who continued with a normal diet were compared in terms of complications, mortality, recurrence, and survival.
RESULTS
RESULTS
The study sample consisted of 68 (84%) male and 13 (16%) female patients, and the mean duration of postoperative follow-up was 31.6 ± 17.9 (4-75) months. Metastasis was identified in eight (17.4%) patients in Grup
CONCLUSION
CONCLUSIONS
Early nutritional supplements should be considered as having a positive effect especially on survival in this specific patient group involving factors with high catabolic effects, such as neoplasia, operation, and chemotherapy together.
Identifiants
pubmed: 37337249
doi: 10.1186/s12957-023-03073-y
pii: 10.1186/s12957-023-03073-y
pmc: PMC10280930
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
183Informations de copyright
© 2023. The Author(s).
Références
J Thorac Cardiovasc Surg. 2020 Jul;160(1):276-285.e1
pubmed: 31859072
Nutr Cancer. 2014;66(8):1362-70
pubmed: 25356861
Asian Cardiovasc Thorac Ann. 2012 Apr;20(2):172-6
pubmed: 22499965
Clin Nutr. 2020 Oct;39(10):3005-3013
pubmed: 32037284
Eur J Cardiothorac Surg. 2019 Jan 1;55(1):91-115
pubmed: 30304509
BMC Cancer. 2022 Nov 24;22(1):1212
pubmed: 36434615
JAMA Netw Open. 2019 Nov 1;2(11):e1915138
pubmed: 31747030
Front Pharmacol. 2018 Mar 22;9:245
pubmed: 29623040
Cent Eur J Immunol. 2020;45(4):454-460
pubmed: 33613095
Support Care Cancer. 2004 Apr;12(4):246-52
pubmed: 14997369
J Cardiothorac Surg. 2016 Jan 19;11:14
pubmed: 26782276
Ann Surg Oncol. 2018 May;25(5):1254-1261
pubmed: 29450756
Radiother Oncol. 2018 Jan;126(1):81-88
pubmed: 29111172
Cancer Manag Res. 2020 Jul 09;12:5597-5605
pubmed: 32753972
J Natl Compr Canc Netw. 2018 Jul;16(7):807-821
pubmed: 30006423
Front Pharmacol. 2016 Nov 03;7:414
pubmed: 27857691
Oncotarget. 2017 Aug 10;8(45):79884-79896
pubmed: 29108370
J Clin Oncol. 2015 Jan 1;33(1):90-9
pubmed: 25422490
Chin Med J (Engl). 2021 Sep 15;134(18):2196-2204
pubmed: 34553701
In Vivo. 2020 Jul-Aug;34(4):1931-1939
pubmed: 32606165
Br J Surg. 2017 Nov;104(12):1594-1608
pubmed: 28940219
Clin Nutr. 2019 Feb;38(1):1-9
pubmed: 30181091
Sci Rep. 2020 Jul 24;10(1):12385
pubmed: 32709867
Clin Nutr. 2017 Feb;36(1):11-48
pubmed: 27637832
Clin Nutr. 2014 Feb;33(1):39-58
pubmed: 23688831
JPEN J Parenter Enteral Nutr. 2020 Jul;44(5):742-767
pubmed: 31709584
Gen Thorac Cardiovasc Surg. 2020 Oct;68(10):1163-1171
pubmed: 32328993
Ann Oncol. 2013 Apr;24(4):986-92
pubmed: 23161898
Lancet Oncol. 2017 Dec;18(12):1610-1623
pubmed: 29129443
Support Care Cancer. 2012 Aug;20(8):1919-28
pubmed: 22314972
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
World J Surg Oncol. 2018 May 11;16(1):90
pubmed: 29751759
Cochrane Database Syst Rev. 2018 Aug 30;8:CD010954
pubmed: 30160300