Perianal extramammary Paget's disease with adenocarcinoma of perianal skin area, a case report.
Paget disease
extramammary Paget disease
rare skin condition
Journal
Journal of surgical case reports
ISSN: 2042-8812
Titre abrégé: J Surg Case Rep
Pays: England
ID NLM: 101560169
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
24
02
2023
accepted:
01
05
2023
medline:
20
6
2023
pubmed:
20
6
2023
entrez:
20
6
2023
Statut:
epublish
Résumé
Extramammary Paget disease (EMPD) is an uncommon slow-growing skin adenocarcinoma originating in the anogenital region and axilla outside the mammary glands, often in regions with apocrine glands. The most common location is the vulva, followed by perineal, perianal, scrotal and penile skin. Here, we report a case of a 63-year-old male with EMPD in the perianal region. He reported 4 years of pain associated with an increasing region of skin irritation and bleeding on defecation that did not improve with topical agents. A biopsy sample revealed poorly differentiated carcinoma consistent with adenocarcinoma and associated with Paget disease. Workup was done. The patient tolerated local excision of the region well with no complications. A rare disease, EMPT, is challenging to diagnose and manage. Histopathological findings can, however, differentiate it from a wide array of similar skin conditions. Thorough investigations should be undertaken before initiating treatment to ensure the best outcomes.
Identifiants
pubmed: 37337540
doi: 10.1093/jscr/rjad291
pii: rjad291
pmc: PMC10276950
doi:
Types de publication
Case Reports
Langues
eng
Pagination
rjad291Informations de copyright
Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023.
Déclaration de conflit d'intérêts
The authors have no conflict of interest to declare.
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