The role of the dentist and the orthodontist in early diagnosis of Gorlin-Goltz syndrome: a cephalometric and photometric study.


Journal

European journal of paediatric dentistry
ISSN: 2035-648X
Titre abrégé: Eur J Paediatr Dent
Pays: Italy
ID NLM: 101121881

Informations de publication

Date de publication:
01 Jun 2023
Historique:
medline: 21 6 2023
pubmed: 20 6 2023
entrez: 20 6 2023
Statut: ppublish

Résumé

The aim of this study was to analyse the facial characteristics and the craniofacial morphology in GGS patients in order to enable an early diagnosis. Gorlin-Goltz syndrome (GGS) is a autosomic dominant disease, characterised by basal cell carcinoma, palmar/plantar pits, maxillary and mandibular keratocysts and dental abnormalities. Nine out of a sample of 24 GGS patients had complete cephalometric and photographic records at an average age of 8.7 years. Cephalometric and photometric analysis were carried out with standard analyses and compared with healthy patients matched for sex and age. Early diagnosis of GGS based on clinical features could be useful to identify the presence of keratocysts through x-ray examination proceeding with surgical removal at an early stage, limiting space occupying damages.

Sections du résumé

AIM OBJECTIVE
The aim of this study was to analyse the facial characteristics and the craniofacial morphology in GGS patients in order to enable an early diagnosis.
BACKGROUND BACKGROUND
Gorlin-Goltz syndrome (GGS) is a autosomic dominant disease, characterised by basal cell carcinoma, palmar/plantar pits, maxillary and mandibular keratocysts and dental abnormalities.
METHODS METHODS
Nine out of a sample of 24 GGS patients had complete cephalometric and photographic records at an average age of 8.7 years. Cephalometric and photometric analysis were carried out with standard analyses and compared with healthy patients matched for sex and age.
CONCLUSION CONCLUSIONS
Early diagnosis of GGS based on clinical features could be useful to identify the presence of keratocysts through x-ray examination proceeding with surgical removal at an early stage, limiting space occupying damages.

Identifiants

pubmed: 37337700
doi: 10.23804/ejpd.2023.24.02.03
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

161-165

Auteurs

M C Meazzini (MC)

DMD, MMSc, Regional Centre for Cleft lip and Palate, Orthodontic Service, Department of Maxillo Facial Surgery, Santi Paolo and Carlo Hospital, Milan.

L P Demonte (LP)

DDS, Regional Centre for Cleft lip and Palate, Orthodontic Service, Department of Maxillo Facial Surgery, Santi Paolo and Carlo Hospital, Milan - Department of Orthodontics, Vita e Salute University, San Raffaele Hospital, Milan.

L Conti (L)

DDS, Regional Centre for Cleft lip and Palate, Orthodontic Service, Department of Maxillo Facial Surgery, Santi Paolo and Carlo Hospital, Milan.

L Autelitano (L)

MD, Regional Centre for Cleft lip and Palate, Department of Maxillo Facial Surgery, Santi Paolo and Carlo Hospital, Milan.

N Cohen (N)

DDS, Regional Centre for Cleft lip and Palate, Orthodontic Service, Department of Maxillo Facial Surgery, Santi Paolo and Carlo Hospital, Milan.

F Mazzoleni (F)

MD, Department of Maxillo Facial Surgery, San Gerardo Hospital, Monza.

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Classifications MeSH