Inflammatory Bowel Disease in Children.

Children Diagnosis Guideline Inflammatory bowel disease Management

Journal

Indian journal of pediatrics
ISSN: 0973-7693
Titre abrégé: Indian J Pediatr
Pays: India
ID NLM: 0417442

Informations de publication

Date de publication:
20 Jun 2023
Historique:
received: 07 11 2022
accepted: 19 04 2023
medline: 20 6 2023
pubmed: 20 6 2023
entrez: 20 6 2023
Statut: aheadofprint

Résumé

Inflammatory bowel disease is an important cause of chronic diarrhea in children, with a rising incidence, globally. The two main subtypes include Crohn's disease and ulcerative colitis. The clinical features are variable, and diagnosis requires initial first-line investigations followed by the involvement of specialist input for targeted imaging and endoscopy with biopsy, to confirm the diagnosis. Despite detailed investigation, inflammatory bowel disease may be clinically indistinguishable from chronic infections such as intestinal tuberculosis, and anti-tuberculosis treatment may be considered prior to further management considerations. The medical management of inflammatory bowel disease depends on subtype classification and severity, and may involve a step-wise approach to immunosuppressive therapies. In children, the consequences of poorly controlled disease are wide ranging, from psychosocial impacts and school non-attendance, to growth impairment and pubertal delay with subsequent impacts on bone health. In addition, an increased need for hospitalization and surgical intervention, and ultimately risk of cancer long-term. A multi-disciplinary team with expertise in inflammatory bowel disease is recommended to mitigate these risks and help to achieve the goal of sustained remission with endoscopic healing. This review focuses on updates on best clinical practice on the diagnosis and management of inflammatory bowel disease in children.

Identifiants

pubmed: 37338669
doi: 10.1007/s12098-023-04671-0
pii: 10.1007/s12098-023-04671-0
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023. Crown.

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Auteurs

Asha Jois (A)

Department of Gastroenterology and Nutrition, Royal Children's Hospital, Melbourne, 50 Flemington Road, Parkville, VIC, 3052, Australia.

George Alex (G)

Department of Gastroenterology and Nutrition, Royal Children's Hospital, Melbourne, 50 Flemington Road, Parkville, VIC, 3052, Australia. george.alex@rch.org.au.
Department of Pediatrics, The University of Melbourne, Parkville, VIC, Australia. george.alex@rch.org.au.

Classifications MeSH