Laser pulse train parameters determine the brightness of a two-photon stimulus.


Journal

Biomedical optics express
ISSN: 2156-7085
Titre abrégé: Biomed Opt Express
Pays: United States
ID NLM: 101540630

Informations de publication

Date de publication:
01 Jun 2023
Historique:
received: 17 03 2023
revised: 21 04 2023
accepted: 28 04 2023
medline: 21 6 2023
pubmed: 21 6 2023
entrez: 21 6 2023
Statut: epublish

Résumé

This report presents the results of measurements of the two-photon vision threshold for various pulse trains. We employed three pulsed near-infrared lasers and pulse stretchers to obtain variations of the pulse duty cycle parameter over three orders of magnitude. We proposed and extensively described a mathematical model that combines the laser parameters with the visual threshold value. The presented methodology enables one to predict the visual threshold value for a two-photon stimulus for a healthy subject while using a laser source of known parameters. Our findings would be of value to laser engineers and the community interested in nonlinear visual perception.

Identifiants

pubmed: 37342710
doi: 10.1364/BOE.489890
pii: 489890
pmc: PMC10278621
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2857-2872

Informations de copyright

© 2023 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement.

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest.

Références

Proc Biol Sci. 2008 Dec 22;275(1653):2777-86
pubmed: 18765346
Nat Biotechnol. 2003 Nov;21(11):1369-77
pubmed: 14595365
Biomed Opt Express. 2020 Dec 17;12(1):462-479
pubmed: 33659083
J Opt Soc Am. 1961 Apr;51:422-9
pubmed: 13752375
Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5445-54
pubmed: 25453064
Invest Ophthalmol Vis Sci. 2021 Dec 1;62(15):23
pubmed: 34935882
J Opt Soc Am. 1947 Jul;37(7):546-54
pubmed: 20256359
J Vis. 2011 Jun 16;11(7):
pubmed: 21680646
Biomed Opt Express. 2020 Sep 15;11(10):5603-5617
pubmed: 33149974
Biomed Opt Express. 2019 Aug 09;10(9):4551-4567
pubmed: 31565509
Diagnostics (Basel). 2022 Mar 21;12(3):
pubmed: 35328313
J Opt Soc Am. 1976 Apr;66(4):339-41
pubmed: 1262982
Biomed Opt Express. 2022 Mar 04;13(4):1899-1911
pubmed: 35519271
Br J Ophthalmol. 1974 Aug;58(8):709-14
pubmed: 4433482

Auteurs

Marcin J Marzejon (MJ)

International Centre for Translational Eye Research, Skierniewicka 10a, 01-230 Warsaw, Poland.
Department of Physical Chemistry of Biological Systems, Institute of Physical Chemistry, Polish Academy of Sciences, M. Kasprzaka 44/52, 01-224 Warsaw, Poland.
Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdańsk University of Technology, G. Narutowicza 11/12, 80-233 Gdańsk, Poland.

Łukasz Kornaszewski (Ł)

International Centre for Translational Eye Research, Skierniewicka 10a, 01-230 Warsaw, Poland.
Department of Physical Chemistry of Biological Systems, Institute of Physical Chemistry, Polish Academy of Sciences, M. Kasprzaka 44/52, 01-224 Warsaw, Poland.

Maciej Wojtkowski (M)

International Centre for Translational Eye Research, Skierniewicka 10a, 01-230 Warsaw, Poland.
Department of Physical Chemistry of Biological Systems, Institute of Physical Chemistry, Polish Academy of Sciences, M. Kasprzaka 44/52, 01-224 Warsaw, Poland.

Katarzyna Komar (K)

International Centre for Translational Eye Research, Skierniewicka 10a, 01-230 Warsaw, Poland.
Department of Physical Chemistry of Biological Systems, Institute of Physical Chemistry, Polish Academy of Sciences, M. Kasprzaka 44/52, 01-224 Warsaw, Poland.
Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Torun, Grudziądzka 5, 87-100 Toruń, Poland.

Classifications MeSH