Optical, structural and antibacterial properties of silver nanoparticles and DNA-templated silver nanoclusters.


Journal

Nanomedicine (London, England)
ISSN: 1748-6963
Titre abrégé: Nanomedicine (Lond)
Pays: England
ID NLM: 101278111

Informations de publication

Date de publication:
04 2023
Historique:
pmc-release: 01 04 2024
medline: 30 6 2023
pubmed: 22 6 2023
entrez: 22 6 2023
Statut: ppublish

Résumé

Silver nanoparticles (AgNPs) are increasingly considered for biomedical applications as drug-delivery carriers, imaging probes and antibacterial agents. Silver nanoclusters (AgNCs) represent another subclass of nanoscale silver. AgNCs are a promising tool for nanomedicine due to their small size, structural homogeneity, antibacterial activity and fluorescence, which arises from their molecule-like electron configurations. The template-assisted synthesis of AgNCs relies on organic molecules that act as polydentate ligands. In particular, single-stranded nucleic acids reproducibly scaffold AgNCs to provide fluorescent, biocompatible materials that are incorporable in other formulations. This mini review outlines the design and characterization of AgNPs and DNA-templated AgNCs, discusses factors that affect their physicochemical and biological properties, and highlights applications of these materials as antibacterial agents and biosensors.

Identifiants

pubmed: 37345552
doi: 10.2217/nnm-2023-0082
pmc: PMC10308257
doi:

Substances chimiques

Silver 3M4G523W1G
Nucleic Acids 0
Anti-Bacterial Agents 0
Drug Carriers 0
DNA 9007-49-2

Types de publication

Journal Article Review Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

769-782

Subventions

Organisme : NIGMS NIH HHS
ID : R35 GM139587
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35GM139587
Pays : United States

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Auteurs

Leyla Danai (L)

Department of Chemistry, Nanoscale Science Program, The University of North Carolina at Charlotte, Charlotte, NC 28223, USA.

Lewis A Rolband (LA)

Department of Chemistry, Nanoscale Science Program, The University of North Carolina at Charlotte, Charlotte, NC 28223, USA.

Valentina Abondano Perdomo (VA)

Physical Sciences Department, West Virginia University Institute of Technology, Beckley, WV 25801, USA.

Elizabeth Skelly (E)

Department of Chemistry, Nanoscale Science Program, The University of North Carolina at Charlotte, Charlotte, NC 28223, USA.

Taejin Kim (T)

Physical Sciences Department, West Virginia University Institute of Technology, Beckley, WV 25801, USA.

Kirill A Afonin (KA)

Department of Chemistry, Nanoscale Science Program, The University of North Carolina at Charlotte, Charlotte, NC 28223, USA.

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Classifications MeSH