Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b.
H5N1
HPAIV
goose/Guangdong
mammal
panzootic
pigs
zoonosis
Journal
Emerging infectious diseases
ISSN: 1080-6059
Titre abrégé: Emerg Infect Dis
Pays: United States
ID NLM: 9508155
Informations de publication
Date de publication:
07 2023
07 2023
Historique:
medline:
26
6
2023
pubmed:
22
6
2023
entrez:
22
6
2023
Statut:
ppublish
Résumé
We found that nasal and alimentary experimental exposure of pigs to highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b was associated with marginal viral replication, without inducing any clinical manifestation or pathological changes. Only 1 of 8 pigs seroconverted, pointing to high resistance of pigs to clade 2.3.4.4b infection.
Identifiants
pubmed: 37347930
doi: 10.3201/eid2907.230296
pmc: PMC10310384
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1492-1495Références
Sci Rep. 2018 Apr 12;8(1):5900
pubmed: 29651056
Emerg Infect Dis. 2010 Oct;16(10):1515-23
pubmed: 20875275
Arch Virol. 2013 Dec;158(12):2531-41
pubmed: 23836394
Euro Surveill. 2023 Jan;28(3):
pubmed: 36695488
BMC Vet Res. 2010 Jan 27;6:4
pubmed: 20105300
Virus Evol. 2022 Aug 25;8(2):veac077
pubmed: 36105667
Microbiol Spectr. 2023 Feb 14;11(1):e0286722
pubmed: 36688676
J Virol. 2005 Aug;79(16):10821-5
pubmed: 16051873
Vaccine. 2022 Oct 12;40(43):6255-6270
pubmed: 36137904