Novel α-mannose-functionalized poly(β-amino ester) nanoparticles as mRNA vaccines with increased antigen presenting cell selectivity in the spleen.

Humans Mannose Spleen COVID-19 Antigen-Presenting Cells Nanoparticles Vaccines RNA, Messenger / genetics

Journal

Journal of materials chemistry. B
ISSN: 2050-7518
Titre abrégé: J Mater Chem B
Pays: England
ID NLM: 101598493

Informations de publication

Date de publication:
12 07 2023
Historique:
medline: 14 7 2023
pubmed: 23 6 2023
entrez: 23 6 2023
Statut: epublish

Résumé

mRNA vaccination has emerged as a prominent therapy for the future of medicine. Despite the colossal advance in this technology and worldwide efficacy proof (

Identifiants

DOI: 10.1039/d3tb00607g PMID: 37350113
pubmed: 37350113
doi: 10.1039/d3tb00607g
doi:

Substances chimiques

poly(beta-amino ester) 0
Mannose PHA4727WTP
Vaccines 0
RNA, Messenger 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

6412-6427

Auteurs

Nil González-Ríos (N)

Grup d'Enginyeria de Materials (Gemat), Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL), 08017 Barcelona, Spain. cristina.fornaguera@iqs.url.edu.
Laboratoy of Biochemistry, Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL), 08017 Barcelona, Spain. magda.faijes@iqs.url.edu.
ORCID: 0000-0003-0726-5282

Margalida Artigues (M)

Analytical and Applied Chemistry Department, Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL), 08017 Barcelona, Spain.

Marta Guerra-Rebollo (M)

Grup d'Enginyeria de Materials (Gemat), Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL), 08017 Barcelona, Spain. cristina.fornaguera@iqs.url.edu.

Antoni Planas (A)

Laboratoy of Biochemistry, Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL), 08017 Barcelona, Spain. magda.faijes@iqs.url.edu.

Salvador Borrós (S)

Grup d'Enginyeria de Materials (Gemat), Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL), 08017 Barcelona, Spain. cristina.fornaguera@iqs.url.edu.
ORCID: 0000-0002-4003-0381

Magda Faijes (M)

Laboratoy of Biochemistry, Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL), 08017 Barcelona, Spain. magda.faijes@iqs.url.edu.

Cristina Fornaguera (C)

Grup d'Enginyeria de Materials (Gemat), Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL), 08017 Barcelona, Spain. cristina.fornaguera@iqs.url.edu.
ORCID: 0000-0002-7014-3213

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Novel α-mannose-functionalized poly(β-amino...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Mannose › Novel α-mannose-functionalized poly(β-amino...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Rate › Novel α-mannose-functionalized poly(β-amino...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Novel α-mannose-functionalized poly(β-amino...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Cellules présentatrices d'antigène › Novel α-mannose-functionalized poly(β-amino...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Novel α-mannose-functionalized poly(β-amino...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Novel α-mannose-functionalized poly(β-amino...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN messager › Novel α-mannose-functionalized poly(β-amino...