Facioscapulohumeral Muscular Dystrophy is Associated With Altered Myoblast Proteome Dynamics.

FSHD biosynthetic labelling deuterium oxide fractional synthesis rate heavy water mitochondria mitochondrial ribosome protein turnover proteome dynamics skeletal muscle

Journal

Molecular & cellular proteomics : MCP
ISSN: 1535-9484
Titre abrégé: Mol Cell Proteomics
Pays: United States
ID NLM: 101125647

Informations de publication

Date de publication:
08 2023
Historique:
received: 15 12 2022
revised: 31 05 2023
accepted: 20 06 2023
medline: 28 8 2023
pubmed: 24 6 2023
entrez: 23 6 2023
Statut: ppublish

Résumé

Proteomic studies in facioscapulohumeral muscular dystrophy (FSHD) could offer new insight into disease mechanisms underpinned by post-transcriptional processes. We used stable isotope (deuterium oxide; D

Identifiants

pubmed: 37353005
pii: S1535-9476(23)00116-0
doi: 10.1016/j.mcpro.2023.100605
pmc: PMC10392138
pii:
doi:

Substances chimiques

Proteome 0
Homeodomain Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

100605

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Yusuke Nishimura (Y)

Research Institute for Sport & Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.

Adam J Bittel (AJ)

Center for Genetic Medicine Research, Children's National Medical Center, Washington, District of Columbia, USA.

Connor A Stead (CA)

Research Institute for Sport & Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.

Yi-Wen Chen (YW)

Center for Genetic Medicine Research, Children's National Medical Center, Washington, District of Columbia, USA. Electronic address: ychen@childrensnational.org.

Jatin G Burniston (JG)

Research Institute for Sport & Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom. Electronic address: j.burniston@ljmu.ac.uk.

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Classifications MeSH