Optimal surgical procedure for treating early-stage adenoid cystic carcinoma of the breast.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
23 06 2023
23 06 2023
Historique:
received:
11
11
2022
accepted:
07
06
2023
medline:
26
6
2023
pubmed:
24
6
2023
entrez:
23
6
2023
Statut:
epublish
Résumé
To explore the superiority of breast conservation surgery (BCS) to mastectomy in treating early-stage adenoid cystic carcinoma of the breast (BACC). Patients with surgically treated stage I/II BACC were enrolled between 2000 and 2019 in the SEER database; they were divided into the BCS and mastectomy groups. Overall survival (OS) and disease-specific survival (DSS) were compared between the two groups, and Cox hazard regression models were used to determine the independent predictors. Of the 583 patients in the study, 386 were included in the BCS group. The 10-year OS rates for the BCS and mastectomy groups were 78% (95% CI: 74-82%) and 76% (95% CI: 70-82%), respectively, but the difference was not statistically significant (p = 0.968). The 10-year DSS rates for the BCS and mastectomy groups were 95% (95% CI: 93-97%) and 89% (95% CI: 85-93%), respectively, and the difference was statistically significant (p = 0.002). Pathological examination of regional lymph nodes and adjuvant treatment were not associated with improved OS or DSS, but age, disease grade, and lymph node metastasis were independent prognostic factors. For stage I/II BACC, BCS can achieve more satisfactory 10-year OS and DSS than mastectomy.
Identifiants
pubmed: 37353590
doi: 10.1038/s41598-023-36644-w
pii: 10.1038/s41598-023-36644-w
pmc: PMC10290055
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
10222Informations de copyright
© 2023. The Author(s).
Références
Eur J Breast Health. 2019 Dec 05;16(1):44-47
pubmed: 31912013
Breast Cancer. 2018 Jan;25(1):28-33
pubmed: 28466440
Ann Surg Oncol. 2021 Apr;28(4):2120-2127
pubmed: 33521897
Cancer Res Treat. 2014 Jan;46(1):93-7
pubmed: 24520228
Am Surg. 2020 Dec;86(12):1684-1690
pubmed: 32845724
Pathol Res Pract. 2017 Apr;213(4):310-315
pubmed: 28222936
Ann Surg Oncol. 2021 Sep;28(9):5039-5047
pubmed: 33492542
Zhonghua Zhong Liu Za Zhi. 2021 Apr 23;43(4):357-382
pubmed: 33902200
BMC Cancer. 2019 May 21;19(1):475
pubmed: 31113416
Cancer Res. 2011 Feb 15;71(4):1214-8
pubmed: 21212413
J Natl Cancer Inst. 2000 Jul 19;92(14):1143-50
pubmed: 10904087
Breast Cancer Res Treat. 2016 Dec;160(3):511-521
pubmed: 27730424
Laryngoscope. 2019 Nov;129(11):2527-2530
pubmed: 30861130
Breast Cancer Res Treat. 2021 Jan;185(2):423-432
pubmed: 33037977
Am J Pathol. 2017 Oct;187(10):2139-2151
pubmed: 28736315
Breast Cancer Res Treat. 2021 Jun;187(3):805-814
pubmed: 33609208
Breast. 2021 Oct;59:358-366
pubmed: 34411836
Breast. 2022 Dec;66:40-48
pubmed: 36113374
J Clin Med. 2022 Jul 31;11(15):
pubmed: 35956093
Acta Otorhinolaryngol Ital. 2021 Aug;41(4):296-307
pubmed: 34533533
Breast. 2017 Feb;31:214-218
pubmed: 27915203
Breast. 2022 Apr;62:144-151
pubmed: 35182994
J Surg Oncol. 2010 Sep 15;102(4):342-7
pubmed: 20589709
Sci Rep. 2017 Aug 23;7(1):9254
pubmed: 28835702
World J Clin Cases. 2014 Dec 16;2(12):732-41
pubmed: 25516849
Sci Rep. 2022 May 19;12(1):8504
pubmed: 35590093
BMC Surg. 2022 Mar 24;22(1):113
pubmed: 35331206
Cancer Commun (Lond). 2021 Nov;41(11):1183-1194
pubmed: 34399040
Acta Clin Croat. 2018 Sep;57(3):497-502
pubmed: 31168183
J Am Coll Surg. 2021 Apr;232(4):607-621
pubmed: 33301909
Diagnostics (Basel). 2022 Jul 21;12(7):
pubmed: 35885663