The lactate dehydrogenase gene is involved in the growth and metabolism of
CRISPR
Lacticaseibacillus paracasei
fermented milk
lactate dehydrogenase
metabolomics
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2023
2023
Historique:
received:
28
03
2023
accepted:
15
05
2023
medline:
26
6
2023
pubmed:
26
6
2023
entrez:
26
6
2023
Statut:
epublish
Résumé
Lactate dehydrogenase (ldh) in lactic acid bacteria is an important enzyme that is involved in the process of milk fermentation. This study aimed to explore the changes and effects of fermented milk metabolites in mutant strains after knocking out the The The results showed that the growth rate and acidification ability of the mutant strain were lower than those of the wild-type strain before the end of fermentation, and analysis of the differential metabolites showed that lactate, L-cysteine, proline, and intermediate metabolites of phenylalanine, tryptophan, and methionine were downregulated ( Our data established a link between the
Identifiants
pubmed: 37362929
doi: 10.3389/fmicb.2023.1195360
pmc: PMC10288368
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1195360Informations de copyright
Copyright © 2023 Fang, Song, Cui, Bai, Lu and Wang.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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