Predictors of prospective suicide attempts in a group at risk of personality disorder following self-poisoning.

alexythimia emergency department personality disorder self-poisoning nonlethal suicide attempt suicidal behavior (SB) suicidal ideation (SI) suicide

Journal

Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006

Informations de publication

Date de publication:
2023
Historique:
received: 30 10 2022
accepted: 16 05 2023
medline: 26 6 2023
pubmed: 26 6 2023
entrez: 26 6 2023
Statut: epublish

Résumé

Patients with personality disorder (PD) are at risk for suicidal behavior and are frequently admitted for this reason to emergency departments. In this context, researchers have tried to identify predictors of their suicidal acts, however, the studies have been mostly retrospective, and uncertainty remains. To prospectively explore factors associated with suicide attempts (SA) in individuals screened for PD from the ecological context of emergencies. Patients were recruited from two emergency departments after a self-poisoning episode ( Having a previous suicidal attempt was linked to a 2.7 times higher chance of recurrence after 6 months, whereas the TAS-20 showed a 1.1 times higher risk at 18 months (OR = 1.1) and the BDI at 24 months (OR = 1.2). Each one-unit increment in TAS-20 and BDI-13 scores increased the risk of SA by 9.8 and 20.4% at 18 and 24 months, respectively. Some clinical features, such as alcohol dependence, suicide intent, and hopelessness, may not be reliable predictors of SA among PD patients. However, in the short term, previous SA and, in the long term, depression and alexithymia may be the most robust clinical predictors to consider in our sample of patients with self-poisoning SA.

Sections du résumé

Background UNASSIGNED
Patients with personality disorder (PD) are at risk for suicidal behavior and are frequently admitted for this reason to emergency departments. In this context, researchers have tried to identify predictors of their suicidal acts, however, the studies have been mostly retrospective, and uncertainty remains. To prospectively explore factors associated with suicide attempts (SA) in individuals screened for PD from the ecological context of emergencies.
Methods UNASSIGNED
Patients were recruited from two emergency departments after a self-poisoning episode (
Results UNASSIGNED
Having a previous suicidal attempt was linked to a 2.7 times higher chance of recurrence after 6 months, whereas the TAS-20 showed a 1.1 times higher risk at 18 months (OR = 1.1) and the BDI at 24 months (OR = 1.2). Each one-unit increment in TAS-20 and BDI-13 scores increased the risk of SA by 9.8 and 20.4% at 18 and 24 months, respectively.
Conclusion UNASSIGNED
Some clinical features, such as alcohol dependence, suicide intent, and hopelessness, may not be reliable predictors of SA among PD patients. However, in the short term, previous SA and, in the long term, depression and alexithymia may be the most robust clinical predictors to consider in our sample of patients with self-poisoning SA.

Identifiants

pubmed: 37363177
doi: 10.3389/fpsyt.2023.1084730
pmc: PMC10289019
doi:

Banques de données

ClinicalTrials.gov
['NCT00641498']

Types de publication

Journal Article

Langues

eng

Pagination

1084730

Informations de copyright

Copyright © 2023 Cailhol, Marcoux, Mathur, Yrondi and Birmes.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Arch Gen Psychiatry. 1961 Jun;4:561-71
pubmed: 13688369
J Pers Disord. 2010 Dec;24(6):773-84
pubmed: 21158599
Swiss Med Wkly. 2019 Feb 04;149:w20016
pubmed: 30715721
J Affect Disord. 1989 Nov-Dec;17(3):203-9
pubmed: 2529288
Acta Psychiatr Scand. 2008 Mar;117(3):177-84
pubmed: 18241308
J Pers Disord. 2020 Jun;34(3):324-347
pubmed: 30307832
Ann Ist Super Sanita. 2004;40(4):475-83
pubmed: 15815115
Compr Psychiatry. 1992 Mar-Apr;33(2):73-7
pubmed: 1544299
Eur Psychiatry. 2015 Sep;30(6):765-9
pubmed: 26138045
Psychol Med. 2001 Jul;31(5):837-45
pubmed: 11459381
J Affect Disord. 2018 Oct 1;238:563-569
pubmed: 29940520
Early Interv Psychiatry. 2020 Jun;14(3):336-342
pubmed: 31402575
Aust N Z J Psychiatry. 2002 Dec;36(6):733-42
pubmed: 12406115
Ann Gen Psychiatry. 2017 Apr 20;16:21
pubmed: 28435437
Psychol Rev. 2010 Apr;117(2):575-600
pubmed: 20438238
Br J Psychiatry. 1981 Nov;139:391-6
pubmed: 7332842
J Clin Psychiatry. 1998;59 Suppl 20:22-33;quiz 34-57
pubmed: 9881538
J Psychiatr Res. 2011 Nov;45(11):1445-52
pubmed: 21722920
Australas Psychiatry. 2015 Apr;23(2):132-5
pubmed: 25616313
J Psychosom Res. 2022 Jun;157:110788
pubmed: 35334350
Br J Psychiatry. 2005 Jan;186:60-6
pubmed: 15630125
Actas Esp Psiquiatr. 2009 May-Jun;37(3):148-52
pubmed: 19533427
Int J Environ Res Public Health. 2018 Mar 30;15(4):
pubmed: 29601506
J Pers Disord. 1998 Summer;12(2):172-8
pubmed: 9661103
Psychiatry Clin Neurosci. 2006 Jun;60(3):289-95
pubmed: 16732744
Am J Psychiatry. 1990 Aug;147(8):1043-8
pubmed: 2197883
Compr Psychiatry. 1989 Mar-Apr;30(2):170-8
pubmed: 2920552
J Affect Disord. 2013 Nov;151(2):474-483
pubmed: 23859005
J Psychosom Res. 1994 Jan;38(1):23-32
pubmed: 8126686
Encephale. 1992 May-Jun;18(3):237-40
pubmed: 1299593
Soc Psychiatry Psychiatr Epidemiol. 2000 Jul;35(7):288-96
pubmed: 11016523
Encephale. 1995 Mar-Apr;21(2):117-22
pubmed: 7781582
Br J Psychiatry. 2013 Sep;203(3):221-7
pubmed: 23887998
Am J Public Health. 2007 Oct;97(10):1842-6
pubmed: 17395838
Int J Psychiatry Clin Pract. 2020 Mar;24(1):83-87
pubmed: 31829763
Medicina (Kaunas). 2020 Jun 13;56(6):
pubmed: 32545811
Eur Psychiatry. 2001 Nov;16(7):379-85
pubmed: 11728849
Psychol Psychother. 2017 Dec;90(4):586-599
pubmed: 28585718
Psychiatry Res. 2020 Jun;288:112920
pubmed: 32279008
J Pers Disord. 2011 Aug;25(4):421-31
pubmed: 21838559
Arch Gen Psychiatry. 2011 Aug;68(8):827-37
pubmed: 21464343
Br J Psychiatry. 2018 Dec;213(6):709-715
pubmed: 30261937
Brain Sci. 2021 Nov 30;11(12):
pubmed: 34942896
Crisis. 2012;33(6):358-63
pubmed: 22759664

Auteurs

Lionel Cailhol (L)

Department of Psychiatry, Institut Universitaire de Santé Mentale de Montréal, CIUSSS of East Montreal, University of Montreal, Montreal, QC, Canada.

Mariève Marcoux (M)

Department of Psychology, University of Montreal, Montreal, QC, Canada.

Anjali Mathur (A)

Department of Brief therapy, University Hospital Center of Toulouse (CHU Toulouse), Toulouse, Occitanie, France.

Antoine Yrondi (A)

Department of Psychiatry and Medical Psychology, University Hospital Center of Toulouse (CHU Toulouse), Expert Centre for Treatment-Resistant Depression FondaMental, ToNIC Toulouse NeuroImaging Centre, Toulouse University, Toulouse, Occitanie, France.

Philippe Birmes (P)

Department of Psychiatry, Psychotherapies and Art Therapy, University Hospital Center of Toulouse (CHU Toulouse), ToNIC Toulouse NeuroImaging Centre, Toulouse University, Toulouse, Occitanie, France.

Classifications MeSH