Incidence of cleft lip and palate, and epidemiology of perinatal deaths related to cleft lip and palate in Hunan Province, China, 2016-2020.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
26 06 2023
Historique:
received: 26 12 2022
accepted: 21 06 2023
medline: 28 6 2023
pubmed: 27 6 2023
entrez: 26 6 2023
Statut: epublish

Résumé

This study aimed to analyze the epidemiological characteristics of cleft lip and/or palate (CL/P) and CL/P-related perinatal deaths, provide some information for intervention programs to reduce the incidence of CL/P and provide clues for future researchers. Data were obtained from the Birth Defects Surveillance System in Hunan Province, China, 2016-2020. Incidences of CL/P [number of cases per 1000 fetuses (births and deaths at 28 weeks of gestation and beyond)] with 95% confidence intervals (CI) were calculated by residence, gender, maternal age, year, and major types [cleft lip only (CL), cleft palate only (CP), and cleft lip with palate (CLP)]. Crude odds ratios (ORs) were calculated to examine the association of each maternal characteristic with CL/P. Pearson chi-square tests (χ

Identifiants

pubmed: 37365256
doi: 10.1038/s41598-023-37436-y
pii: 10.1038/s41598-023-37436-y
pmc: PMC10293189
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

10304

Informations de copyright

© 2023. The Author(s).

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Auteurs

Xu Zhou (X)

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China. chzhouxu@163.com.

Yurong Jiang (Y)

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China. jyr0822@126.com.

Junqun Fang (J)

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China. 40112079@qq.com.

Hua Wang (H)

The Hunan Children's Hospital, Changsha, 410000, Hunan Province, China. wanghua213@aliyun.com.
National Health Commission Key Laboratory of Birth Defects Research, Prevention and Treatment, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China. wanghua213@aliyun.com.

Donghua Xie (D)

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China.

Haiyan Kuang (H)

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China.

Ting Li (T)

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China.

Qin Liu (Q)

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China.

Jian He (J)

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410000, Hunan Province, China.

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