Cognitive Functions, Depressive and Anxiety Symptoms After One Year of CPAP Treatment in Obstructive Sleep Apnea.
CPAP treatment
Trail Making Test
Verbal Fluency Test
cognitive functions
depression
obstructive sleep apnoea
treatment efficacy
Journal
Psychology research and behavior management
ISSN: 1179-1578
Titre abrégé: Psychol Res Behav Manag
Pays: New Zealand
ID NLM: 101514563
Informations de publication
Date de publication:
2023
2023
Historique:
received:
21
03
2023
accepted:
22
05
2023
medline:
27
6
2023
pubmed:
27
6
2023
entrez:
27
6
2023
Statut:
epublish
Résumé
The study worked with depressive symptoms, anxiety score and cognitive functions in obstructive sleep apnea (OSA) patients treated with CPAP. Eighty-one subjects with OSA and without psychiatric comorbidity were treated with CPAP for one year and completed the following scales and cognitive tests: Trail Making Test, Verbal Fluency Test, d2 Test, Beck Depression Inventory-II and Beck Anxiety Inventory. MINI ruled out psychiatric disorder. At the two months check-up, subjects were re-evaluated for depressive and anxiety symptoms, and after one year of CPAP treatment, subjects repeated cognitive tests and scales. Data about therapy adherence and effectiveness were obtained from the patient's CPAP machines. The study was completed by 59 CPAP adherent patients and eight non-adherent patients. CPAP therapy effectiveness was verified in all patients by decreasing the apnea-hypopnoea index below 5 and/or 10% of baseline values. The adherent patients significantly improved depressive and anxiety symptoms. There was also an improvement in overall performance in the attention test; however, performance in many individual items did not change. The adherent patients also improved verbal fluency and in the Part B of the Trail making test. The non-adherent group significantly increased the number of mistakes made in the d2 test; other results were non-significant. According to our results, OSA patients' mood, anxiety and certain cognitive domains improved during the one-year therapy with CPAP. NCT03866161.
Identifiants
pubmed: 37366480
doi: 10.2147/PRBM.S411465
pii: 411465
pmc: PMC10290842
doi:
Banques de données
ClinicalTrials.gov
['NCT03866161']
Types de publication
Journal Article
Langues
eng
Pagination
2253-2266Informations de copyright
© 2023 Vanek et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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