The Association of Methylation Level in the
CYP39A1
CpG
DNA methylation
HAPE
the Chinese population
Journal
Pharmacogenomics and personalized medicine
ISSN: 1178-7066
Titre abrégé: Pharmgenomics Pers Med
Pays: New Zealand
ID NLM: 101514107
Informations de publication
Date de publication:
2023
2023
Historique:
received:
28
11
2022
accepted:
07
06
2023
medline:
27
6
2023
pubmed:
27
6
2023
entrez:
27
6
2023
Statut:
epublish
Résumé
High altitude pulmonary edema (HAPE) is still the most common fatal disease at high altitudes. DNA methylation proceeds with an important role in HAPE progression. This study was designed to investigate the association between Peripheral blood samples were enrolled from 106 participants (53 HAPE patients and 53 healthy subjects) to study the association of Probability analysis showed that the methylation probabilities of CYP39A1_1_CpG_5 and CYP39A1_3_CpG_21 are significant differences between the cases and controls ( The methylation level of
Sections du résumé
Background
UNASSIGNED
High altitude pulmonary edema (HAPE) is still the most common fatal disease at high altitudes. DNA methylation proceeds with an important role in HAPE progression. This study was designed to investigate the association between
Methods
UNASSIGNED
Peripheral blood samples were enrolled from 106 participants (53 HAPE patients and 53 healthy subjects) to study the association of
Results
UNASSIGNED
Probability analysis showed that the methylation probabilities of CYP39A1_1_CpG_5 and CYP39A1_3_CpG_21 are significant differences between the cases and controls (
Conclusion
UNASSIGNED
The methylation level of
Identifiants
pubmed: 37366513
doi: 10.2147/PGPM.S397862
pii: 397862
pmc: PMC10290841
doi:
Types de publication
Journal Article
Langues
eng
Pagination
617-628Informations de copyright
© 2023 Wang et al.
Déclaration de conflit d'intérêts
There were not any competing interests.
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