Cyanobacteria: A Promising Source of Antifungal Metabolites.
action mechanism
alkaloids
antifungal agents
cyanobacteria
peptides
secondary metabolites
Journal
Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729
Informations de publication
Date de publication:
14 Jun 2023
14 Jun 2023
Historique:
received:
21
04
2023
revised:
23
05
2023
accepted:
27
05
2023
medline:
29
6
2023
pubmed:
27
6
2023
entrez:
27
6
2023
Statut:
epublish
Résumé
Cyanobacteria are a rich source of secondary metabolites, and they have received a great deal of attention due to their applicability in different industrial sectors. Some of these substances are known for their notorious ability to inhibit fungal growth. Such metabolites are very chemically and biologically diverse. They can belong to different chemical classes, including peptides, fatty acids, alkaloids, polyketides, and macrolides. Moreover, they can also target different cell components. Filamentous cyanobacteria have been the main source of these compounds. This review aims to identify the key features of these antifungal agents, as well as the sources from which they are obtained, their major targets, and the environmental factors involved when they are being produced. For the preparation of this work, a total of 642 documents dating from 1980 to 2022 were consulted, including patents, original research, review articles, and theses.
Identifiants
pubmed: 37367684
pii: md21060359
doi: 10.3390/md21060359
pmc: PMC10300848
pii:
doi:
Substances chimiques
Antifungal Agents
0
Anti-Bacterial Agents
0
Macrolides
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Fundação Amazônia Paraense de Amparo a Estudos e Pesquisas
ID : 03/2019
Organisme : Coordenação de Aperfeicoamento de Pessoal de Nível Superior
ID : 001
Références
J Nat Prod. 2021 Feb 26;84(2):278-286
pubmed: 33444023
J Nat Prod. 2001 Feb;64(2):154-8
pubmed: 11429991
Org Lett. 2005 Mar 31;7(7):1375-8
pubmed: 15787510
Carbohydr Res. 2012 Jul 1;355:40-4
pubmed: 22647542
Planta Med. 2009 Oct;75(13):1427-30
pubmed: 19431099
Biochim Biophys Acta Biomembr. 2019 Aug 1;1861(8):1510-1521
pubmed: 31226245
Mar Drugs. 2020 Apr 10;18(4):
pubmed: 32290087
Mar Drugs. 2019 May 10;17(5):
pubmed: 31083354
J Nat Prod. 2007 Feb;70(2):196-201
pubmed: 17315959
J Antibiot (Tokyo). 1992 Sep;45(9):1458-66
pubmed: 1429232
Mar Drugs. 2020 Mar 18;18(3):
pubmed: 32197482
Org Lett. 2009 Nov 19;11(22):5330-3
pubmed: 19860385
J Basic Microbiol. 2008 Jun;48(3):186-94
pubmed: 18506903
Interdiscip Sci. 2014 Mar;6(1):63-70
pubmed: 24464706
Curr Top Membr. 2020;86:143-184
pubmed: 33837692
J Nat Prod. 2020 Jun 26;83(6):1885-1890
pubmed: 32479093
ISME J. 2021 Jan;15(1):211-227
pubmed: 32943748
Experientia. 1989 Feb 15;45(2):115-21
pubmed: 2493387
Toxins (Basel). 2018 Apr 13;10(4):
pubmed: 29652856
PLoS One. 2020 Apr 22;15(4):e0224051
pubmed: 32320394
BMC Genomics. 2014 Nov 18;15:977
pubmed: 25404466
Foods. 2020 Oct 12;9(10):
pubmed: 33053649
Life (Basel). 2015 Jan 21;5(1):269-93
pubmed: 25615610
J Nat Prod. 1990 Nov-Dec;53(6):1533-42
pubmed: 2128517
J Nat Prod. 2000 May;63(5):611-5
pubmed: 10843570
Cancer Lett. 1996 Oct 1;107(1):53-7
pubmed: 8913266
Bioorg Med Chem. 2015 Jul 1;23(13):3153-62
pubmed: 26001342
J Nat Prod. 2018 Feb 23;81(2):410-413
pubmed: 29432010
Bioorg Med Chem. 2004 Apr 15;12(8):1955-62
pubmed: 15051063
Open Forum Infect Dis. 2020 Jan 12;7(2):ofaa016
pubmed: 32099843
Appl Environ Microbiol. 2013 Apr;79(8):2642-7
pubmed: 23396340
J Nat Prod. 2005 May;68(5):695-700
pubmed: 15921412
Toxins (Basel). 2021 Feb 09;13(2):
pubmed: 33572271
Cancers (Basel). 2021 Nov 12;13(22):
pubmed: 34830812
FEBS Lett. 2005 Sep 26;579(23):5157-62
pubmed: 16146629
Cell Mol Biol (Noisy-le-grand). 2014 Dec 24;60(5):82-9
pubmed: 25535717
PLoS One. 2013 Apr 12;8(4):e60894
pubmed: 23593345
Plants (Basel). 2021 Apr 07;10(4):
pubmed: 33917252
J Antibiot (Tokyo). 2016 Apr;69(4):348-51
pubmed: 26932409
Microbiol Res. 2006;161(2):180-6
pubmed: 16427523
Chembiochem. 2020 Mar 16;21(6):845-852
pubmed: 31769581
Mar Drugs. 2017 Jul 01;15(7):
pubmed: 28671564
Arch Microbiol. 1992;157(5):406-10
pubmed: 1510566
J Pept Sci. 2017 Jul;23(7-8):514-531
pubmed: 28661555
Phytochemistry. 2007 Nov-Dec;68(22-24):2722-35
pubmed: 17643453
Beilstein J Org Chem. 2014 Aug 07;10:1808-16
pubmed: 25161741
Lipids. 2004 Nov;39(11):1101-13
pubmed: 15726825
Mar Drugs. 2021 Mar 15;19(3):
pubmed: 33804177
Angew Chem Int Ed Engl. 2021 Apr 26;60(18):10064-10072
pubmed: 33599093
J Nat Prod. 2022 Jul 22;85(7):1704-1714
pubmed: 35793792
Appl Environ Microbiol. 2010 May;76(9):2769-77
pubmed: 20228117
Biochem Genet. 2013 Oct;51(9-10):766-79
pubmed: 23839085
Mar Drugs. 2021 Nov 12;19(11):
pubmed: 34822504
Mycoses. 2020 Oct;63(10):1021-1032
pubmed: 32744334
Org Lett. 2021 Jan 1;23(1):102-106
pubmed: 33305960
Biochem Biophys Res Commun. 2006 Oct 20;349(2):740-9
pubmed: 16949033
Sci Rep. 2017 Jan 24;7:41181
pubmed: 28117406
Mar Drugs. 2016 Apr 06;14(4):
pubmed: 27058546
Nat Struct Biol. 2003 Dec;10(12):1058-63
pubmed: 14578936
Mar Drugs. 2020 Jul 15;18(7):
pubmed: 32679743
J Nat Prod. 2007 Apr;70(4):499-503
pubmed: 17311455
Mar Drugs. 2020 Nov 28;18(12):
pubmed: 33260719
Arch Microbiol. 1998 Jan;169(1):10-9
pubmed: 9396830
Front Microbiol. 2021 Nov 04;12:684565
pubmed: 34803938
Elife. 2021 Jun 15;10:
pubmed: 34127188
Chem Res Toxicol. 2012 Jun 18;25(6):1203-11
pubmed: 22551534
Stand Genomic Sci. 2018 Oct 12;13:26
pubmed: 30344889
J Basic Microbiol. 2013 Mar;53(3):201-13
pubmed: 22733581
Bioresour Technol. 2020 Oct;313:123700
pubmed: 32590305
J Nat Prod. 2002 Jun;65(6):866-71
pubmed: 12088429
Biomed Pharmacother. 2021 Jun;138:111495
pubmed: 33765586
Nat Commun. 2019 Feb 1;10(1):545
pubmed: 30710081
Chem Biol Interact. 1996 Dec 20;102(3):183-91
pubmed: 9021170
Toxins (Basel). 2020 Dec 21;12(12):
pubmed: 33371249
Org Lett. 2002 May 30;4(11):1883-6
pubmed: 12027638
Toxins (Basel). 2014 Jun 23;6(6):1929-50
pubmed: 24960202
J Antibiot (Tokyo). 2017 May;70(5):708-709
pubmed: 28270686
Org Lett. 2006 Feb 16;8(4):737-40
pubmed: 16468755
PLoS One. 2014 Nov 04;9(11):e111904
pubmed: 25369527
Photosynth Res. 2018 Nov;138(2):177-189
pubmed: 30027501
J Biol Chem. 1996 Mar 15;271(11):6192-8
pubmed: 8626409
Mar Drugs. 2017 Nov 10;15(11):
pubmed: 29125580
Bioessays. 2006 Aug;28(8):799-808
pubmed: 16927300
Molecules. 2020 Sep 01;25(17):
pubmed: 32882989
Toxins (Basel). 2021 Jul 27;13(8):
pubmed: 34437393
Biochim Biophys Acta. 2012 Dec;1818(12):3000-9
pubmed: 22842546
J Chromatogr A. 2016 Mar 18;1438:76-83
pubmed: 26893022
Curr Top Med Chem. 2008;8(2):141-51
pubmed: 18289083
J Nat Prod. 2000 Oct;63(10):1437-9
pubmed: 11076573
Evolution. 2012 Sep;66(9):2961-8
pubmed: 22946816
Mar Drugs. 2021 Jun 23;19(7):
pubmed: 34201595
Mar Life Sci Technol. 2021 May 19;3(4):488-518
pubmed: 37073258
Microbiol Res. 2008;163(3):307-13
pubmed: 16872816
Nat Rev Mol Cell Biol. 2018 Jul;19(7):451-463
pubmed: 29674711
Aquat Toxicol. 2013 Apr 15;130-131:9-17
pubmed: 23333903
J Appl Phycol. 2018 Feb;30(1):375-384
pubmed: 30294068
Tetrahedron Lett. 2014 Jan 15;55(3):686-689
pubmed: 25225453
Int J Biol Macromol. 2017 Dec;105(Pt 2):1501-1510
pubmed: 28602983
Mar Drugs. 2020 Sep 22;18(9):
pubmed: 32972038
Microorganisms. 2022 Jan 27;10(2):
pubmed: 35208762
J Nat Prod. 1992 May;55(5):613-9
pubmed: 1517734
J Nat Prod. 1998 Oct;61(10):1304-6
pubmed: 9784177
J Nat Prod. 2009 May 22;72(5):894-9
pubmed: 19371071
Bioorg Med Chem. 2012 Sep 1;20(17):5290-5
pubmed: 22863526
J Antibiot (Tokyo). 2020 Aug;73(8):526-533
pubmed: 32235860
Chemotherapy. 2010;56(4):318-24
pubmed: 20714150
J Org Chem. 2002 Nov 15;67(23):8210-5
pubmed: 12423153
Ecotoxicol Environ Saf. 2020 Apr 1;192:110313
pubmed: 32066007
J Phycol. 2011 Aug;47(4):955-62
pubmed: 27020030
Microorganisms. 2021 Apr 02;9(4):
pubmed: 33918311
Phytochemistry. 2001 Jun;57(4):613-9
pubmed: 11394868
J Nat Prod. 2015 Aug 28;78(8):1957-62
pubmed: 26204500
Beilstein J Org Chem. 2019 Jul 11;15:1545-1551
pubmed: 31354873
J Nat Prod. 2007 Dec;70(12):1977-86
pubmed: 18001088
Nat Prod Rep. 2012 Mar;29(3):372-91
pubmed: 22237837
Phytochemistry. 2010 Dec;71(17-18):2116-23
pubmed: 20965528
Food Chem. 2016 May 15;199:114-8
pubmed: 26775951
J Fungi (Basel). 2016 Oct 02;2(4):
pubmed: 29376943
Front Oncol. 2014 Jun 18;4:153
pubmed: 24995158
J Nat Prod. 2007 May;70(5):730-5
pubmed: 17432902
Biotechnol Adv. 2019 May - Jun;37(3):422-443
pubmed: 30797095
Biomed Pharmacother. 2017 Jun;90:760-776
pubmed: 28419973
Phytochemistry. 2016 Feb;122:113-118
pubmed: 26632528
Nat Rev Microbiol. 2018 Aug;16(8):471-483
pubmed: 29946124
Chem Res Toxicol. 2015 Feb 16;28(2):216-24
pubmed: 25621379
Water Res. 2021 May 15;196:117017
pubmed: 33765498
J Nat Prod. 2019 Sep 27;82(9):2608-2619
pubmed: 31468974
PLoS Pathog. 2021 Apr 22;17(4):e1009470
pubmed: 33886695
Philos Trans R Soc Lond B Biol Sci. 2010 Mar 12;365(1541):749-63
pubmed: 20124342
J Nat Prod. 2011 Aug 26;74(8):1737-43
pubmed: 21751786
Anal Bioanal Chem. 2017 Feb;409(4):917-930
pubmed: 27904937
Biochem Biophys Res Commun. 2018 Jan 8;495(2):1782-1788
pubmed: 29229390
J Nat Prod. 1998 May;61(5):677-80
pubmed: 9599278
Chembiochem. 2021 May 14;22(10):1790-1799
pubmed: 33527693
Appl Microbiol Biotechnol. 1995 Aug-Sep;43(4):692-700
pubmed: 7546607
J Nat Prod. 1999 Sep;62(9):1333-5
pubmed: 10514329
Appl Environ Microbiol. 2019 Feb 6;85(4):
pubmed: 30504214
Toxins (Basel). 2014 Dec 22;6(12):3568-81
pubmed: 25533520
Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13669-74
pubmed: 26474830
J Nat Prod. 2014 Jun 27;77(6):1287-96
pubmed: 24937366
Mycoses. 2005 Nov;48(6):365-77
pubmed: 16262871
Crit Rev Microbiol. 2009;35(4):271-82
pubmed: 19863381
Plant Physiol. 2000 Nov;124(3):1027-38
pubmed: 11080280
Org Biomol Chem. 2021 Mar 18;19(10):2302-2311
pubmed: 33629091
Plants (Basel). 2020 Nov 27;9(12):
pubmed: 33261092
Cancer Res. 1994 Jul 15;54(14):3779-84
pubmed: 7913408
J Nat Prod. 2005 Apr;68(4):604-6
pubmed: 15844960
Mar Drugs. 2021 Jan 04;19(1):
pubmed: 33406599
Aust Vet J. 1992 Jul;69(7):163-5
pubmed: 1445080
Chem Biol. 2005 Mar;12(3):287-91
pubmed: 15797212
AIMS Microbiol. 2017 Aug 4;3(3):689-705
pubmed: 31294182
J Nat Prod. 2017 Oct 27;80(10):2708-2715
pubmed: 29019684
Toxins (Basel). 2019 Dec 24;12(1):
pubmed: 31878347
Trends Cell Biol. 2018 Oct;28(10):776-792
pubmed: 29871823
Appl Microbiol Biotechnol. 2018 Sep;102(17):7351-7363
pubmed: 29982925
J Nat Prod. 2013 Sep 27;76(9):1781-8
pubmed: 24016099
Mar Drugs. 2015 Dec 05;13(12):7285-300
pubmed: 26690181
Nat Prod Rep. 2021 Sep 23;38(9):1567-1588
pubmed: 34032254
J Nat Prod. 2005 Dec;68(12):1793-5
pubmed: 16378379
Phytochemistry. 2020 Dec;180:112529
pubmed: 33032099
J Nat Prod. 2015 Mar 27;78(3):534-8
pubmed: 25536090
Environ Toxicol Pharmacol. 2006 Jan;21(1):42-50
pubmed: 21783637
Bioorg Med Chem Lett. 2008 Aug 1;18(15):4413-5
pubmed: 18606541
Semin Diagn Pathol. 2019 May;36(3):177-181
pubmed: 31010605
J Antibiot (Tokyo). 1992 Sep;45(9):1451-7
pubmed: 1429231
J Med Chem. 2014 Dec 11;57(23):9718-39
pubmed: 25207470
Int J Cancer Res (Tortola). 2015 Mar;49(1):1655-1662
pubmed: 26753095
Org Biomol Chem. 2021 Jun 30;19(25):5577-5588
pubmed: 34085692
J Nat Prod. 2005 Mar;68(3):459-61
pubmed: 15787461
Int J Biochem Cell Biol. 2012 Feb;44(2):266-74
pubmed: 22108200
In Vivo. 2005 May-Jun;19(3):577-82
pubmed: 15875779
J Med Chem. 2007 Mar 22;50(6):1266-79
pubmed: 17323939
J Appl Toxicol. 2020 Dec 2;:
pubmed: 33289164
Chembiochem. 2020 Aug 3;21(15):2170-2177
pubmed: 32182403
European J Org Chem. 2012 Sep 1;2012(27):5141-5150
pubmed: 24574859
Sci Total Environ. 2020 Mar 25;710:136314
pubmed: 31923677
Mar Drugs. 2016 Jan 20;14(1):21
pubmed: 26805858
Front Microbiol. 2019 Feb 12;10:214
pubmed: 30809213
RSC Adv. 2021 Sep 16;11(49):30873-30886
pubmed: 35498921
Mar Drugs. 2019 May 30;17(6):
pubmed: 31151260
Molecules. 2018 Oct 16;23(10):
pubmed: 30332796
ACS Chem Biol. 2020 Nov 20;15(11):2929-2936
pubmed: 33143417
ACS Chem Biol. 2014 Feb 21;9(2):372-7
pubmed: 24180436
Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1909-17
pubmed: 24742428
Mar Drugs. 2015 Apr 13;13(4):2124-40
pubmed: 25871291
Alkaloids Chem Biol. 2001;57:75-184
pubmed: 11705123
Cell Rep. 2018 Apr 17;23(3):667-672
pubmed: 29669272
PLoS One. 2012;7(7):e41222
pubmed: 22829929
Harmful Algae. 2020 Jun;96:101849
pubmed: 32560836
Front Microbiol. 2019 Nov 21;10:2573
pubmed: 31824443
Org Lett. 2002 Apr 18;4(8):1307-10
pubmed: 11950349
Physiol Plant. 2021 Oct;173(2):639-650
pubmed: 34145585
BMC Genomics. 2012 Nov 13;13:613
pubmed: 23148582
Bioorg Med Chem. 2018 May 15;26(9):2310-2319
pubmed: 29606488
J Nat Prod. 2011 Jul 22;74(7):1597-605
pubmed: 21699148
Comp Biochem Physiol C Toxicol Pharmacol. 2004 Dec;139(4):231-8
pubmed: 15683832
Front Microbiol. 2020 Sep 16;11:578878
pubmed: 33042096
Nat Prod Rep. 2016 Feb;33(2):348-64
pubmed: 26758451
Bioorg Med Chem Lett. 2006 Aug 15;16(16):4220-2
pubmed: 16777415
Chemosphere. 2006 Oct;65(4):604-8
pubmed: 16554083
Bioresour Technol. 2019 Apr;278:424-434
pubmed: 30685131
Mini Rev Med Chem. 2010 Sep;10(10):946-55
pubmed: 21034416
Appl Biochem Biotechnol. 2015 Aug;176(8):2279-89
pubmed: 26100389
Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11183-8
pubmed: 20534563
J Nat Prod. 2009 Nov;72(11):2043-5
pubmed: 19888742
Cell Motil Cytoskeleton. 1993;24(1):39-48
pubmed: 8319266
Front Plant Sci. 2020 Oct 16;11:579807
pubmed: 33178246
Bioorg Med Chem. 2019 May 15;27(10):1966-1980
pubmed: 30929947
Alkaloids Chem Biol. 2014;73:65-160
pubmed: 26521649
Front Microbiol. 2018 Feb 26;9:306
pubmed: 29535689
J Nat Prod. 2004 Aug;67(8):1403-6
pubmed: 15332864
FEMS Microbiol Rev. 2006 Jul;30(4):530-63
pubmed: 16774586
J Org Chem. 2018 Mar 16;83(6):3034-3046
pubmed: 29457979
European J Org Chem. 2004 May;2004(10):2131-2141
pubmed: 30443158
Appl Environ Microbiol. 2001 Dec;67(12):5833-9
pubmed: 11722942
Chembiochem. 2016 Mar 15;17(6):466-70
pubmed: 26749394
Mol Biosyst. 2011 Apr;7(4):1205-16
pubmed: 21258753
Microorganisms. 2021 Jul 27;9(8):
pubmed: 34442672
Org Lett. 2018 Sep 7;20(17):5238-5241
pubmed: 30141631
J Biol Chem. 2021 Jan-Jun;296:100621
pubmed: 33811856
Nat Rev Microbiol. 2019 Jan;17(1):37-50
pubmed: 30410070
J Nat Prod. 2019 Mar 22;82(3):680-685
pubmed: 30835122
Toxins (Basel). 2020 Apr 11;12(4):
pubmed: 32290496
Mar Drugs. 2019 May 20;17(5):
pubmed: 31137530
J Antibiot (Tokyo). 2015 Mar;68(3):165-77
pubmed: 25182484
Chemosphere. 2020 Jun;248:125961
pubmed: 32059332
ACS Chem Biol. 2017 Jul 21;12(7):1796-1804
pubmed: 28489343
J Fungi (Basel). 2019 Jul 20;5(3):
pubmed: 31330862
mBio. 2010 May 18;1(1):
pubmed: 20689745
Chin J Nat Med. 2014 Jun;12(6):401-6
pubmed: 24969519