Development of Positively Charged Poly-L-Lysine Magnetic Nanoparticles as Potential MRI Contrast Agent.
MRI
enhancement
magnetic fluid
magnetite nanoparticles
poly-L-lysine
relative contrast
relaxation time
relaxivity
relaxometry
superparamagnetic behavior
Journal
Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216
Informations de publication
Date de publication:
09 Jun 2023
09 Jun 2023
Historique:
received:
18
05
2023
revised:
05
06
2023
accepted:
06
06
2023
medline:
27
6
2023
pubmed:
27
6
2023
entrez:
27
6
2023
Statut:
epublish
Résumé
A colloidal solution of magnetic nanoparticles (MNPs) modified with biocompatible positively charged poly-L-lysine (PLL) with an oleate (OL) layer employed as an initial coating was produced as a potential MRI contrast agent. The effect of various PLL/MNPs' mass ratios on the samples' hydrodynamic diameter, zeta potential, and isoelectric point (IEP) was studied by the dynamic light-scattering method. The optimal mass ratio for MNPs' surface coating was 0.5 (sample PLL
Identifiants
pubmed: 37368261
pii: nano13121831
doi: 10.3390/nano13121831
pmc: PMC10305316
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Operational Programme Integrated Infrastructure co-funded by ERDF
ID : ITMS 313011AUW7 "NANOVIR"
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