Elucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2).
Journal
NPJ Parkinson's disease
ISSN: 2373-8057
Titre abrégé: NPJ Parkinsons Dis
Pays: United States
ID NLM: 101675390
Informations de publication
Date de publication:
27 Jun 2023
27 Jun 2023
Historique:
received:
01
12
2022
accepted:
15
05
2023
medline:
28
6
2023
pubmed:
28
6
2023
entrez:
27
6
2023
Statut:
epublish
Résumé
The Monogenic Network of the Global Parkinson's Genetics Program (GP2) aims to create an efficient infrastructure to accelerate the identification of novel genetic causes of Parkinson's disease (PD) and to improve our understanding of already identified genetic causes, such as reduced penetrance and variable clinical expressivity of known disease-causing variants. We aim to perform short- and long-read whole-genome sequencing for up to 10,000 patients with parkinsonism. Important features of this project are global involvement and focusing on historically underrepresented populations.
Identifiants
pubmed: 37369645
doi: 10.1038/s41531-023-00526-9
pii: 10.1038/s41531-023-00526-9
pmc: PMC10300084
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2023. The Author(s).
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