Does the Environmental Air Impact the Condition of the Vomeronasal Organ? A Mouse Model for Intensive Farming.
alteration
ammonia
environmental air
histology
vomeronasal organ
Journal
Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614
Informations de publication
Date de publication:
07 Jun 2023
07 Jun 2023
Historique:
received:
17
05
2023
revised:
02
06
2023
accepted:
06
06
2023
medline:
28
6
2023
pubmed:
28
6
2023
entrez:
28
6
2023
Statut:
epublish
Résumé
Chemical communication in mammals is ensured by exchanging chemical signals through the vomeronasal organ (VNO) and its ability to detect pheromones. The alteration of this organ has been proven to impact animal life, participating in the onset of aggressive behaviors in social groups. To date, few studies have highlighted the possible causes leading to these alterations, and the farming environment has not been investigated, even though irritant substances such as ammonia are known to induce serious damage in the respiratory tract. The goal of this study was to investigate the environmental impact on the VNO structure. Thirty mice were split into three groups, one housed in normal laboratory conditions and the other two in confined environments, with or without the release of litter ammonia. VNOs were analyzed using histology and immunohistochemistry to evaluate the effect of different environments on their condition. Both restricted conditions induced VNO alterations (
Identifiants
pubmed: 37370413
pii: ani13121902
doi: 10.3390/ani13121902
pmc: PMC10294897
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
J Am Assoc Lab Anim Sci. 2008 Mar;47(2):57-62
pubmed: 18351723
Life (Basel). 2021 Jan 04;11(1):
pubmed: 33406620
Curr Opin Allergy Clin Immunol. 2015 Apr;15(2):137-44
pubmed: 25636160
Vet Med Int. 2010 Aug 29;2010:
pubmed: 20871868
Toxicol Appl Pharmacol. 1984 Jul;74(3):417-29
pubmed: 6740688
Laryngoscope. 2000 Jul;110(7):1071-7
pubmed: 10892672
J Am Assoc Lab Anim Sci. 2011 Nov;50(6):868-78
pubmed: 22330779
Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12898-903
pubmed: 21768373
J Anim Sci. 1975 Sep;41(3):735-9
pubmed: 1158807
J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):16-29
pubmed: 26786204
J Clin Invest. 2020 Nov 2;130(11):6034-6040
pubmed: 32780721
J Am Assoc Lab Anim Sci. 2014 Mar;53(2):146-51
pubmed: 24602540
J Neurosci Res. 2005 Jan 1-15;79(1-2):74-80
pubmed: 15578727
Am J Rhinol Allergy. 2010 May-Jun;24(3):192-6
pubmed: 20537285
Cold Spring Harb Perspect Biol. 2011 Jun 01;3(6):
pubmed: 21502308
Prog Neurobiol. 2003 Jun;70(3):245-318
pubmed: 12951145
Nature. 2011 Sep 21;478(7368):241-5
pubmed: 21937988
Arch Environ Health. 1972 Sep;25(3):158-65
pubmed: 5048233
Biol Reprod. 2000 Sep;63(3):953-8
pubmed: 10952943
ORL J Otorhinolaryngol Relat Spec. 1998 Mar-Apr;60(2):88-91
pubmed: 9553974
Cell. 1995 Oct 20;83(2):195-206
pubmed: 7585937
Front Vet Sci. 2022 Sep 12;9:936838
pubmed: 36172609
Nature. 2009 May 28;459(7246):574-7
pubmed: 19387439
Animals (Basel). 2022 Jan 26;12(3):
pubmed: 35158627
Chem Senses. 2007 Jan;32(1):57-64
pubmed: 17071943
Int J Mol Sci. 2020 Jun 17;21(12):
pubmed: 32560306
J Feline Med Surg. 2016 Dec;18(12):997-1002
pubmed: 26404027
Animals (Basel). 2021 Apr 22;11(5):
pubmed: 33922332
J Appl Toxicol. 2014 Mar;34(3):250-7
pubmed: 23576315
Ecotoxicol Environ Saf. 2022 Sep 1;242:113913
pubmed: 35907323
Sci Rep. 2019 Sep 25;9(1):13821
pubmed: 31554873
Behav Neurosci. 2006 Aug;120(4):925-36
pubmed: 16893298
Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5135-5143
pubmed: 30804203
J Neurosci. 2016 Mar 9;36(10):2995-3006
pubmed: 26961953
Mol Aspects Med. 2015 Dec;46:70-7
pubmed: 26344371
Sci Rep. 2017 Feb 03;7:41807
pubmed: 28155917
J Am Assoc Lab Anim Sci. 2015 Sep;54(5):478-86
pubmed: 26424245
Microsc Res Tech. 2002 Aug 1;58(3):251-60
pubmed: 12203702
Front Neuroanat. 2014 Oct 13;8:114
pubmed: 25352786
J Steroid Biochem Mol Biol. 1991 Oct;39(4B):661-9
pubmed: 1892795
Cell. 2003 Mar 7;112(5):607-18
pubmed: 12628182