Plasma Osteopontin Reflects Tissue Damage in Acute Pancreatitis.
acute pancreatitis
biomarker
organ damage
osteopontin
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
03 Jun 2023
03 Jun 2023
Historique:
received:
25
04
2023
revised:
31
05
2023
accepted:
31
05
2023
medline:
28
6
2023
pubmed:
28
6
2023
entrez:
28
6
2023
Statut:
epublish
Résumé
Several scoring systems for clinical prediction of the severity of acute pancreatitis (AP) have been proposed. Yet, there is still a need for an easy-to-measure biomarker. Osteopontin (OPN) may be released to the circulation early during tissue injury, but the significance of OPN in AP has not yet been established. We aimed to evaluate plasma levels of OPN in relation to the severity of AP. In 39 individuals with confirmed AP, plasma was collected on the day of admission and consecutively for three days thereafter. Sex- and age-matched healthy blood donors (
Identifiants
pubmed: 37371722
pii: biomedicines11061627
doi: 10.3390/biomedicines11061627
pmc: PMC10295411
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Swedish Rheumatism Association
ID : R-939149
Organisme : Region Östergötland
ID : ALF grants
Organisme : Gustafsson Foundation
ID : 2022
Organisme : King Gustaf V's 80-year Anniversary foundation
ID : FAI-2020-0663
Organisme : King Gustaf V and Queen Victoria's Freemasons foundation
ID : 2022
Références
Gut. 2013 Jan;62(1):102-11
pubmed: 23100216
JAMA. 2021 Jan 26;325(4):382-390
pubmed: 33496779
Gastroenterol Rep (Oxf). 2018 May;6(2):127-131
pubmed: 29780601
Clin Biochem. 2017 Dec;50(18):1275-1280
pubmed: 28720341
J Chronic Dis. 1987;40(5):373-83
pubmed: 3558716
Crit Rev Clin Lab Sci. 2015;52(6):273-83
pubmed: 26173077
Pancreas. 2018 Mar;47(3):e7-e10
pubmed: 29424811
Pancreas. 2022 May 1;51(5):e77-e79
pubmed: 35973019
Lupus Sci Med. 2017 Jul 28;4(1):e000225
pubmed: 29188073
J Clin Med. 2021 Dec 13;10(24):
pubmed: 34945133
J Cell Commun Signal. 2009 Dec;3(3-4):311-22
pubmed: 19798593
Bone. 2006 Jun;38(6):749-57
pubmed: 16412713
J Transl Autoimmun. 2021 Jun 10;4:100106
pubmed: 34179742
Crit Care Med. 1995 Oct;23(10):1638-52
pubmed: 7587228
Science. 2000 Feb 4;287(5454):860-4
pubmed: 10657301
J Autoimmun. 2004 Jun;22(4):315-23
pubmed: 15120755
Clin Exp Rheumatol. 2022 Jan-Feb;40(1):173-182
pubmed: 34128791
J Rheumatol. 2019 May;46(5):492-500
pubmed: 30647177
Arthritis Res Ther. 2013 Jan 23;15(1):R18
pubmed: 23343383
Intensive Care Med. 2008 Dec;34(12):2176-84
pubmed: 18807011
Radiology. 1994 Nov;193(2):297-306
pubmed: 7972730