Exploring the Association of Burning Mouth Syndrome with Depressive and Anxiety Disorders in Middle-Aged and Older Adults: A Systematic Review.

anxiety burning mouth syndrome depression middle age older people

Journal

Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269

Informations de publication

Date de publication:
19 Jun 2023
Historique:
received: 27 04 2023
revised: 15 06 2023
accepted: 15 06 2023
medline: 28 6 2023
pubmed: 28 6 2023
entrez: 28 6 2023
Statut: epublish

Résumé

Burning Mouth Syndrome (BMS) is an idiopathic condition mainly affecting middle-aged and older individuals with hormonal disturbances or psychiatric disorders and is characterized by chronic pain. The etiopathogenesis of this multifactorial syndrome is largely unknown. The objective of the present systematic review was therefore to evaluate the relationship of BMS with depressive and anxiety disorders in middle-aged and older individuals. We selected studies evaluating BMS and depressive and anxiety disorders assessed with validated tools, published from their inception up to April 2023, using PubMed, MEDLINE, EMBASE, Scopus, Ovid, and Google Scholar databases and adhering to the PRISMA 2020 guidelines/PRISMA 2020 27-item checklist. This study is registered on PROSPERO (CRD42023409595). The National Institutes of Health Quality Assessment Toolkits for Observational Cohort and Cross-Sectional Studies were used to examine the risk of bias. Two independent investigators rated 4322 records against the primary endpoint and found 7 records meeting the eligibility requirements. Anxiety disorders were found to be the most common psychiatric disorders related to BMS (63.7%), followed by depressive disorders (36.3%). We found a moderate association of BMS with anxiety disorders, with multiple studies included ( In middle-aged and older subjects, anxiety and depressive disorders may be potentially related to the development of BMS. Furthermore, also in these age groups, females showed higher risk of developing BMS than males, even when taking into account multimorbidity such as sleep disorders, personality traits, and biopsychosocial changes as suggested by study-specific findings.

Sections du résumé

BACKGROUND BACKGROUND
Burning Mouth Syndrome (BMS) is an idiopathic condition mainly affecting middle-aged and older individuals with hormonal disturbances or psychiatric disorders and is characterized by chronic pain. The etiopathogenesis of this multifactorial syndrome is largely unknown. The objective of the present systematic review was therefore to evaluate the relationship of BMS with depressive and anxiety disorders in middle-aged and older individuals.
METHODS METHODS
We selected studies evaluating BMS and depressive and anxiety disorders assessed with validated tools, published from their inception up to April 2023, using PubMed, MEDLINE, EMBASE, Scopus, Ovid, and Google Scholar databases and adhering to the PRISMA 2020 guidelines/PRISMA 2020 27-item checklist. This study is registered on PROSPERO (CRD42023409595). The National Institutes of Health Quality Assessment Toolkits for Observational Cohort and Cross-Sectional Studies were used to examine the risk of bias.
RESULTS RESULTS
Two independent investigators rated 4322 records against the primary endpoint and found 7 records meeting the eligibility requirements. Anxiety disorders were found to be the most common psychiatric disorders related to BMS (63.7%), followed by depressive disorders (36.3%). We found a moderate association of BMS with anxiety disorders, with multiple studies included (
CONCLUSIONS CONCLUSIONS
In middle-aged and older subjects, anxiety and depressive disorders may be potentially related to the development of BMS. Furthermore, also in these age groups, females showed higher risk of developing BMS than males, even when taking into account multimorbidity such as sleep disorders, personality traits, and biopsychosocial changes as suggested by study-specific findings.

Identifiants

pubmed: 37374003
pii: jpm13061014
doi: 10.3390/jpm13061014
pmc: PMC10305447
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Vittorio Dibello (V)

Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari Aldo Moro, 70124 Bari, Italy.

Andrea Ballini (A)

Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

Madia Lozupone (M)

Neurodegenerative Disease Unit, Department of D-BRAIN, University of Bari Aldo Moro, 70124 Bari, Italy.

Carlo Custodero (C)

"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari Aldo Moro, 70124 Bari, Italy.

Stefania Cantore (S)

Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Independent Researcher, 70124 Bari, Italy.

Rodolfo Sardone (R)

Unit of Research Methodology and Data Sciences for Population Health, National Institute of Gastroenterology "Saverio de Bellis", Research Hospital, Castellana Grotte, 70013 Bari, Italy.

Antonio Dibello (A)

Stella Maris Nursing Home and Day Care Center, Monopoli, 70043 Bari, Italy.

Filippo Santarcangelo (F)

Independent Researcher, 70124 Bari, Italy.

Bianca Barulli Kofler (B)

"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari Aldo Moro, 70124 Bari, Italy.

Massimo Petruzzi (M)

Interdisciplinary Department of Medicine, Section of Dentistry, University of Bari Aldo Moro, 70124 Bari, Italy.

Antonio Daniele (A)

Institute of Neurology, Catholic University of Sacred Heart, 00168 Rome, Italy.
Institute of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.

Vincenzo Solfrizzi (V)

"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari Aldo Moro, 70124 Bari, Italy.

Francesco Panza (F)

Unit of Research Methodology and Data Sciences for Population Health, National Institute of Gastroenterology "Saverio de Bellis", Research Hospital, Castellana Grotte, 70013 Bari, Italy.

Classifications MeSH