Detection of Three Opioids (Morphine, Codeine and Methadone) and Their Metabolites (6-Monoacetylmorphine and 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) in Larvae of
6-MAM
EDDP
Lucilia sericata
UHPLC-FT-MS
codeine
forensic entomotoxicology
larvae
methadone
morphine
post-mortem
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
08 Jun 2023
08 Jun 2023
Historique:
received:
12
04
2023
revised:
31
05
2023
accepted:
06
06
2023
medline:
29
6
2023
pubmed:
28
6
2023
entrez:
28
6
2023
Statut:
epublish
Résumé
Insects on corpses could be a useful tool for the detection of exogenous substances such as drugs of abuse. The identification of exogenous substances in carrion insects is critical for proper estimation of the postmortem interval. It also provides information about the deceased person that may prove useful for forensic purposes. High-performance liquid chromatography coupled with Fourier transform mass spectrometry is a highly sensitive analytical technique that can identify substances even at very low concentrations, such as in the case of searching for exogenous substances in larvae. In this paper, a method is proposed for the identification of morphine, codeine, methadone, 6-monoacetylmorphine (6-MAM) and 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) in the larvae of
Identifiants
pubmed: 37375203
pii: molecules28124649
doi: 10.3390/molecules28124649
pmc: PMC10304931
pii:
doi:
Substances chimiques
Methadone
UC6VBE7V1Z
Analgesics, Opioid
0
Codeine
UX6OWY2V7J
Morphine
76I7G6D29C
2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
Z3LC48U94I
6-O-monoacetylmorphine
M5E47P1ZCH
Morphine Derivatives
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
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