New Hydrogels Nanocomposites Based on Chitosan, 2-Formylphenylboronic Acid, and ZnO Nanoparticles as Promising Disinfectants for Duodenoscopes Reprocessing.
ZnO
boronic aldehyde
chitosan hydrogels
disinfectant
Journal
Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357
Informations de publication
Date de publication:
13 Jun 2023
13 Jun 2023
Historique:
received:
22
05
2023
revised:
09
06
2023
accepted:
12
06
2023
medline:
28
6
2023
pubmed:
28
6
2023
entrez:
28
6
2023
Statut:
epublish
Résumé
New hydrogels nanocomposites, based on iminoboronate hydrogels and ZnO nanoparticles (ZnO-NPs), were obtained and characterised in order to develop a new class of disinfectants able to fight the nosocomial infections produced by duodenoscopes investigation procedures. The formation of the imine linkages between chitosan and the aldehyde was demonstrated using NMR and FTIR spectroscopy, while the supramolecular architecture of the developed systems was evaluated via wide-angle X-ray diffraction and polarised optical microscopy. The morphological characterisation of the systems via scanning electron microscopy revealed the highly porous structure of the materials, in which no ZnO agglomeration could be observed, indicating the very fine and homogenous encapsulation of the nanoparticles into the hydrogels. The newly synthetised hydrogels nanocomposites was proven to have synergistic antimicrobial properties, being very efficient as disinfectants against reference strains as:
Identifiants
pubmed: 37376315
pii: polym15122669
doi: 10.3390/polym15122669
pmc: PMC10302584
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Ministry of Research, Innovation and Digitization, CNCS - UEFISCDI
ID : PN-III-P1-1.1-TE-2021-0739
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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