Coronary Microvascular Spasm: Clinical Presentation and Diagnosis.
Coronary microvascular dysfunction
coronary microvascular spasm
coronary vasospasm
endothelial function
endothelium-dependent hyperpolarization
inflammation
nitric oxide
Journal
European cardiology
ISSN: 1758-3764
Titre abrégé: Eur Cardiol
Pays: England
ID NLM: 101574780
Informations de publication
Date de publication:
2023
2023
Historique:
received:
29
09
2022
accepted:
13
10
2022
medline:
28
6
2023
pubmed:
28
6
2023
entrez:
28
6
2023
Statut:
epublish
Résumé
Professor Maseri pioneered the research and treatment of coronary vasomotion abnormalities represented by coronary vasospasm and coronary microvascular dysfunction (CMD). These mechanisms can cause myocardial ischaemia even in the absence of obstructive coronary artery disease, and have been appreciated as an important aetiology and therapeutic target with major clinical implications in patients with ischaemia with non-obstructive coronary artery disease (INOCA). Coronary microvascular spasm is one of the key mechanisms responsible for myocardial ischaemia in patients with INOCA. Comprehensive assessment of coronary vasomotor reactivity by invasive functional coronary angiography or interventional diagnostic procedure is recommended to identify the underlying mechanisms of myocardial ischaemia and to tailor the best treatment and management based on the endotype of INOCA. This review highlights the pioneering works of Professor Maseri and contemporary research on coronary vasospasm and CMD with reference to endothelial dysfunction, Rho-kinase activation and inflammation.
Identifiants
pubmed: 37377449
doi: 10.15420/ecr.2022.50
pmc: PMC10291603
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e07Informations de copyright
Copyright © 2023, Radcliffe Cardiology.
Déclaration de conflit d'intérêts
Disclosure: HS is on the editorial board of European Cardiology Review; this did not influence peer review. All other authors have no conflicts of interest to declare. Funding: This work was supported, in part, by the Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology, Tokyo, Japan (21K16044).
Références
JAMA Netw Open. 2020 Feb 5;3(2):e1921326
pubmed: 32058558
Heart. 2022 Dec 22;109(2):88-95
pubmed: 35318254
Int J Cardiol. 2001 Dec;81(2-3):151-6
pubmed: 11744131
Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1492-1500
pubmed: 31018659
J Am Coll Cardiol. 2016 Feb 9;67(5):598-600
pubmed: 26846957
Eur Heart J. 2014 May;35(17):1101-11
pubmed: 24366916
Acta Physiol (Oxf). 2017 Jan;219(1):22-96
pubmed: 26706498
N Engl J Med. 1991 Mar 7;324(10):648-54
pubmed: 1994247
Lancet. 1998 Apr 18;351(9110):1165-9
pubmed: 9643687
Prog Cardiovasc Dis. 1982 Nov-Dec;25(3):169-92
pubmed: 6755554
Science. 1983 Aug 5;221(4610):560-2
pubmed: 6408736
J Am Coll Cardiol. 2006 Feb 7;47(3 Suppl):S4-S20
pubmed: 16458170
N Engl J Med. 1990 Aug 23;323(8):514-20
pubmed: 2115977
J Clin Invest. 1962 Nov;41:2075-85
pubmed: 14035509
J Clin Invest. 1996 Feb 1;97(3):769-76
pubmed: 8609234
Arterioscler Thromb Vasc Biol. 2020 May;40(5):1400-1412
pubmed: 32237907
Circ J. 2009 Mar;73(3):394-403
pubmed: 19202303
Cardiovasc Res. 2022 Jun 29;118(8):e57-e58
pubmed: 35653604
Biochem Exp Biol. 1977;13(3):291-7
pubmed: 16296011
J Am Coll Cardiol. 2010 Jun 22;55(25):2825-32
pubmed: 20579539
Br Med J. 1957 Jul 27;2(5038):173-9
pubmed: 13446433
Lancet. 1983 Apr 2;1(8327):746-9
pubmed: 6132091
Arch Intern Med. 2009 May 11;169(9):843-50
pubmed: 19433695
Eur Heart J. 2021 Jan 20;42(3):228-239
pubmed: 33477168
Circulation. 1996 Dec 15;94(12):3341-7
pubmed: 8989149
J Am Coll Cardiol. 2021 Sep 28;78(13):1352-1371
pubmed: 34556322
Int J Cardiol. 2019 Dec 15;297:8-13
pubmed: 31611086
Int J Cardiol. 2018 Jan 1;250:16-20
pubmed: 29031990
JACC Cardiovasc Interv. 2015 Sep;8(11):1445-1453
pubmed: 26404197
Chest. 1980 Jul;78(1 Suppl):210-5
pubmed: 7398409
Clin Res Cardiol. 2020 Feb;109(2):246-254
pubmed: 31236694
N Engl J Med. 2015 Dec 10;373(24):2314-24
pubmed: 26549714
Circulation. 2017 Mar 14;135(11):1075-1092
pubmed: 28289007
J Cardiovasc Pharmacol. 1996 Nov;28(5):703-11
pubmed: 8945685
J Cardiovasc Pharmacol. 2004 Sep;44(3):275-7
pubmed: 15475822
Eur Heart J. 2021 Nov 21;42(44):4592-4600
pubmed: 34038937
Eur Heart J Qual Care Clin Outcomes. 2019 Oct 1;5(4):283-291
pubmed: 31168622
J Am Coll Cardiol. 2019 Nov 12;74(19):2350-2360
pubmed: 31699275
JACC Cardiovasc Imaging. 2023 Jan;16(1):63-74
pubmed: 36115814
EuroIntervention. 2020 Aug 28;16(5):387-394
pubmed: 31403459
J Am Heart Assoc. 2022 Apr 5;11(7):e023207
pubmed: 35301851
Eur Heart J Acute Cardiovasc Care. 2020 Jun 08;:2048872620932422
pubmed: 32508106
Lancet. 1983 Oct 1;2(8353):753-8
pubmed: 6137600
Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):97-107
pubmed: 26543099
Circulation. 2014 Jun 17;129(24):2518-27
pubmed: 24787469
JACC Cardiovasc Interv. 2022 Jan 10;15(1):65-75
pubmed: 34991826
J Am Coll Cardiol. 2002 Mar 6;39(5):847-51
pubmed: 11869851
Eur Heart J. 2019 May 7;40(18):1426-1435
pubmed: 30561616
Am J Physiol Heart Circ Physiol. 2006 Sep;291(3):H1138-46
pubmed: 16648191
J Am Coll Cardiol. 1999 May;33(6):1453-61
pubmed: 10334408
Eur Heart J. 2017 Feb 14;38(7):489-496
pubmed: 27694191
J Am Coll Cardiol. 2017 Nov 7;70(19):2349-2358
pubmed: 29096805
Circulation. 1991 Dec;84(6):2307-12
pubmed: 1959186
Int J Angiol. 2020 Dec;29(4):250-255
pubmed: 33268976
Eur Rev Med Pharmacol Sci. 2018 Oct;22(19):6545-6550
pubmed: 30338825
Circulation. 2014 Apr 29;129(17):1723-30
pubmed: 24573349
Eur Cardiol. 2021 Sep 03;16:e30
pubmed: 34603510
Am J Cardiol. 1979 Oct 22;44(5):788-92
pubmed: 386762
Eur Heart J. 2015 Jan 21;36(4):228-37
pubmed: 25189599
Eur Heart J Case Rep. 2022 Feb 16;6(2):ytac083
pubmed: 35669198
JAMA. 2014 Nov 5;312(17):1754-63
pubmed: 25369489
Am Heart J. 2013 Jul;166(1):134-41
pubmed: 23816032
J Cardiovasc Pharmacol. 1989;13 Suppl 5:S177-9
pubmed: 2473301
N Engl J Med. 1994 Aug 18;331(7):417-24
pubmed: 7880233
J Am Coll Cardiol. 1991 Feb;17(2):499-506
pubmed: 1991909
J Am Coll Cardiol. 1989 Mar 15;13(4):860-72
pubmed: 2522463
J Clin Invest. 1997 Dec 1;100(11):2793-9
pubmed: 9389744
J Vis Exp. 2021 Sep 17;(175):
pubmed: 34605803
J Am Heart Assoc. 2020 May 5;9(9):e014954
pubmed: 32345133
Circulation. 1976 Aug;54(2):280-8
pubmed: 939025
N Engl J Med. 2007 Feb 22;356(8):830-40
pubmed: 17314342
J Clin Invest. 2000 Dec;106(12):1521-30
pubmed: 11120759
Circ Res. 2003 Feb 7;92(2):e31-40
pubmed: 12574154
J Am Coll Cardiol. 2011 Sep 13;58(12):1231-7
pubmed: 21903056
Lancet. 1984 Dec 15;2(8416):1353-7
pubmed: 6150363
Heart Vessels. 2022 Jun;37(6):931-941
pubmed: 35059807
J Am Heart Assoc. 2012 Oct;1(5):e002485
pubmed: 23316292
Am J Med. 1981 Apr;70(4):752-4
pubmed: 7211910
J Cardiovasc Pharmacol. 2005 Nov;46(5):622-6
pubmed: 16220069
Am Heart J. 1978 Oct;96(4):554-5
pubmed: 696575
N Engl J Med. 2020 Apr 9;382(15):1395-1407
pubmed: 32227755
Lancet. 1977 Apr 2;1(8014):713-7
pubmed: 66516
Circulation. 2004 Feb 17;109(6):722-5
pubmed: 14970106
Eur Heart J. 2012 Mar;33(6):734-44
pubmed: 21911339
Circulation. 2015 Mar 24;131(12):1054-60
pubmed: 25712205
Circulation. 2003 Feb 25;107(7):1040-5
pubmed: 12600919
N Engl J Med. 2017 Sep 21;377(12):1119-1131
pubmed: 28845751
Eur Heart J. 2020 Oct 1;41(37):3504-3520
pubmed: 32626906
N Engl J Med. 2010 Mar 11;362(10):886-95
pubmed: 20220183
J Am Coll Cardiol. 2003 Jan 1;41(1):15-9
pubmed: 12570938
J Cardiol. 2008 Oct;52(2):67-78
pubmed: 18922380
J Am Coll Cardiol. 2012 Feb 14;59(7):655-62
pubmed: 22322081
Nat Rev Cardiol. 2015 Jan;12(1):48-62
pubmed: 25311229
J Am Coll Cardiol. 2009 Dec 8;54(24):2321-9
pubmed: 19958969
J Am Heart Assoc. 2020 Apr 21;9(8):e015515
pubmed: 32301366
Lancet. 1987 May 9;1(8541):1057-9
pubmed: 2883396
Am J Cardiol. 1989 Oct 15;64(14):956-8
pubmed: 2679033
Eur Heart J. 2020 Jan 14;41(3):407-477
pubmed: 31504439
J Card Fail. 2020 Nov;26(11):1016-1021
pubmed: 32846205
Br Heart J. 1979 Feb;41(2):167-74
pubmed: 371644
N Engl J Med. 1978 Dec 7;299(23):1271-7
pubmed: 714095
Am J Cardiol. 1976 Nov 23;38(6):751-60
pubmed: 998514
Lancet. 2018 Jan 6;391(10115):31-40
pubmed: 29103656
J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2841-2855
pubmed: 30266608
JAMA. 2018 Nov 6;320(17):1764-1773
pubmed: 30398602
Eur Heart J. 2014 Dec 1;35(45):3180-93
pubmed: 25354517
J Nucl Biol Med. 1972 Oct-Dec;16(4):259-66
pubmed: 4580695
J Am Coll Cardiol. 2007 Sep 25;50(13):1272-8
pubmed: 17888845
Eur Heart J. 2018 Jan 7;39(2):91-98
pubmed: 29228159
J Am Coll Cardiol. 2006 Feb 7;47(3 Suppl):S21-9
pubmed: 16458167
Lancet. 1951 Nov 10;2(6689):845-50
pubmed: 14881483
JACC Cardiovasc Interv. 2021 Mar 22;14(6):606-618
pubmed: 33736768
J Am Coll Cardiol. 2018 Jan 30;71(4):414-425
pubmed: 29389358
Circ Res. 2016 Jan 22;118(2):352-66
pubmed: 26838319
Eur Cardiol. 2021 Mar 30;16:e13
pubmed: 33897839
Eur Heart J. 2018 Jun 14;39(23):2135-2146
pubmed: 29688324
Am J Cardiol. 1978 Dec;42(6):1019-35
pubmed: 727129
Circulation. 2008 Apr 8;117(14):1787-801
pubmed: 18378615