The Emerging Role of Ketamine in Acute Postoperative Pain Management.

Humans Ketamine / therapeutic use Analgesics / therapeutic use Analgesics, Opioid / therapeutic use Pain, Postoperative / drug therapy
Acute pain Ketamine Opioids Pain Postoperative pain

Journal

Current pain and headache reports
ISSN: 1534-3081
Titre abrégé: Curr Pain Headache Rep
Pays: United States
ID NLM: 100970666

Informations de publication

Date de publication:
Sep 2023
Historique:
accepted: 11 05 2023
medline: 29 8 2023
pubmed: 28 6 2023
entrez: 28 6 2023
Statut: ppublish

Résumé

Postoperative pain (POP) is among the most unpleasant experiences that patients face after surgery. Interest in and use of N-methyl-D-aspartate (NMDA) receptor antagonists for the management of POP has increased over the years with ketamine being the most popular drug of this class. Several randomized controlled trials found that the use of ketamine either alone or in combination with other medications leads to decreased postoperative pain and opioid consumption. However, there are other studies that have not found these benefits. The results as of now suggest that the role of intraoperative ketamine in postoperative pain control varies among different operative procedures. While some studies have shown promise in ketamine's potential use as a postoperative analgesic, there is still a great deal of proposed research and randomized controlled trials needed to deduce the most efficacious and tolerable form and dose of ketamine.

Identifiants

DOI: 10.1007/s11916-023-01134-1 PMID: 37378786
pubmed: 37378786
doi: 10.1007/s11916-023-01134-1
pii: 10.1007/s11916-023-01134-1
doi:

Substances chimiques

Ketamine 690G0D6V8H
Analgesics 0
Analgesics, Opioid 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

387-397

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Auteurs

Amber N Edinoff (AN)

Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Boston, MA, 02114, USA. aedinoff@mgh.harvard.edu.
Louisiana Addiction Research Center, Shreveport, LA, 71103, USA. aedinoff@mgh.harvard.edu.
ORCID: 0000-0001-7436-6206

Dorothy Askins (D)

Department of Anesthesiology, Tulane University School of Medicine, 1415 Tulane Ave, New Orleans, LA, 70112, USA.

Elena Bobo (E)

Tulane University School of Medicine, 1415 Tulane Ave, New Orleans, LA, 70112, USA.

Kathryn L White (KL)

School of Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.

Zahaan Eswani (Z)

School of Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.

Eric D Jackson (ED)

University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.

Danielle M Wenger (DM)

University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.

Aaron J Kaye (AJ)

Department of Anesthesiology, Medical University of South Carolina, 135 Rutledge Ave # 9, Charleston, SC, 29425, USA.

Elyse M Cornett (EM)

Louisiana Addiction Research Center, Shreveport, LA, 71103, USA.
Department of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.

Adam M Kaye (AM)

Department of Pharmacy Practice, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA, 95211, USA.

Alan D Kaye (AD)

Louisiana Addiction Research Center, Shreveport, LA, 71103, USA.
Department of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Emerging Role of Ketamine in Acute...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures alicycliques › Cyclohexanes › Kétamine › The Emerging Role of Ketamine in Acute...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Analgésiques › The Emerging Role of Ketamine in Acute...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Dépresseurs du système nerveux central › Stupéfiants › Analgésiques morphiniques › The Emerging Role of Ketamine in Acute...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations neurologiques › Douleur postopératoire › The Emerging Role of Ketamine in Acute...