Treatment Guidelines for Hyponatremia: Stay the Course.
Journal
Clinical journal of the American Society of Nephrology : CJASN
ISSN: 1555-905X
Titre abrégé: Clin J Am Soc Nephrol
Pays: United States
ID NLM: 101271570
Informations de publication
Date de publication:
28 Jun 2023
28 Jun 2023
Historique:
received:
09
05
2023
accepted:
22
06
2023
pubmed:
28
6
2023
medline:
28
6
2023
entrez:
28
6
2023
Statut:
aheadofprint
Résumé
International guidelines designed to minimize the risk of complications that can occur when correcting severe hyponatremia have been widely accepted for a decade. On the basis of the results of a recent large retrospective study of patients hospitalized with hyponatremia, it has been suggested that hyponatremia guidelines have gone too far in limiting the rate of rise of the serum sodium concentration; the need for therapeutic caution and frequent monitoring of the serum sodium concentration has been questioned. These assertions are reminiscent of a controversy that began many years ago. After reviewing the history of that controversy, the evidence supporting the guidelines, and the validity of data challenging them, we conclude that current safeguards should not be abandoned. To do so would be akin to discarding your umbrella because you remained dry in a rainstorm. The authors of this review, who represent 20 medical centers in nine countries, have all contributed significantly to the literature on the subject. We urge clinicians to continue to treat severe hyponatremia cautiously and to wait for better evidence before adopting less stringent therapeutic limits.
Identifiants
pubmed: 37379081
doi: 10.2215/CJN.0000000000000244
pii: 01277230-990000000-00180
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Investigateurs
Richard H Sterns
(RH)
Helbert Rondon-Berrios
(H)
Horacio J Adrogue
(HJ)
Tomas Berl
(T)
Volker Burst
(V)
David M Cohen
(DM)
Mirjam Christ-Crain
(M)
Martin Cuesta
(M)
Decaux Guy
(D)
Michael Emmett
(M)
Aoife Garrahy
(A)
Fabrice Gankam-Kengne
(F)
John K Hix
(JK)
Ewout J Hoorn
(EJ)
Kamel S Kamel
(KS)
Nicolaos E Madias
(NE)
Alessandro Peri
(A)
Julie Refardt
(J)
Mitchell H Rosner
(MH)
Mark Sherlock
(M)
Stephen M Silver
(SM)
Alain Soupart
(A)
Chris J Thompson
(CJ)
Joseph G Verbalis
(JG)
Informations de copyright
Copyright © 2023 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of American Society of Nephrology.
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