Aquaporin 5 in the eye: Expression, function, and roles in ocular diseases.
AQP5
Cornea
Lacrimal gland
Lens
Journal
Experimental eye research
ISSN: 1096-0007
Titre abrégé: Exp Eye Res
Pays: England
ID NLM: 0370707
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
received:
05
01
2023
revised:
26
05
2023
accepted:
25
06
2023
medline:
23
10
2023
pubmed:
29
6
2023
entrez:
28
6
2023
Statut:
ppublish
Résumé
As a water channel protein, aquaporin 5 (AQP5) is essential for the maintenance of the normal physiological functions of ocular tissues. This review provides an overview of the expression and function of AQP5 in the eye and discusses their role in related eye diseases. Although AQP5 plays a vital role in ocular functions, such as maintaining corneal and lens transparency, regulating water movement, and maintaining homeostasis, some of its functions in ocular tissues are still unclear. Based on the key role of AQP5 in eye function, this review suggests that in the future, eye diseases may be treated by regulating the expression of aquaporin.
Identifiants
pubmed: 37380095
pii: S0014-4835(23)00178-1
doi: 10.1016/j.exer.2023.109557
pii:
doi:
Substances chimiques
Aquaporin 5
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
109557Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest None.