Bacterial Infections in Acute on Chronic Liver Failure.

Humans Acute-On-Chronic Liver Failure Bacterial Infections / complications
Acute on chronic liver failure Liver cirrhosis Liver transplantation Sepsis Septic shock

Journal

Clinics in liver disease
ISSN: 1557-8224
Titre abrégé: Clin Liver Dis
Pays: United States
ID NLM: 9710002

Informations de publication

Date de publication:
08 2023
Historique:
medline: 30 6 2023
pubmed: 29 6 2023
entrez: 28 6 2023
Statut: ppublish

Résumé

Bacterial infections (BIs) are the most common precipitating event of acute-on-chronic liver failure (ACLF) and a frequent complication of ACLF. BIs aggravate the course of the syndrome and are associated with higher mortality rates. For this reason, BIs should be promptly diagnosed and treated in all patients with ACLF. The administration of an appropriate empirical antibiotic therapy improves survival in patients with BIs and ACLF and is the cornerstone of treatment. Due to the spread of antibiotic resistance worldwide, the empirical treatment should cover multi-drug-resistant organisms. Herein we reviewed the current evidence about the management of BIs in ACLF.

Identifiants

DOI: 10.1016/j.cld.2023.03.013 PMID: 37380293
pubmed: 37380293
pii: S1089-3261(23)00046-6
doi: 10.1016/j.cld.2023.03.013
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

703-716

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Simone Incicco (S)

Department of Medicine (DIMED), Unit of Internal Medicine and Hepatology (UIMH), University Hospital of Padova, Via Giustiniani 2, Padova 35128, Italy.

Paolo Angeli (P)

Department of Medicine (DIMED), Unit of Internal Medicine and Hepatology (UIMH), University Hospital of Padova, Via Giustiniani 2, Padova 35128, Italy.

Salvatore Piano (S)

Department of Medicine (DIMED), Unit of Internal Medicine and Hepatology (UIMH), University Hospital of Padova, Via Giustiniani 2, Padova 35128, Italy. Electronic address: salvatorepiano@gmail.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Bacterial Infections in Acute on Chronic Liver Failure.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Insuffisance hépatique › Défaillance hépatique › Défaillance hépatique aigüe › Insuffisance hépatique aigüe sur chronique › Bacterial Infections in Acute on Chronic Liver Failure.
questionsmedicales.fr › Infection › Infections bactériennes et mycoses › Infections bactériennes › Bacterial Infections in Acute on Chronic Liver Failure.