Management of the Zenker diverticulum: multicenter retrospective comparative study of open surgery and rigid endoscopy versus flexible endoscopy.


Journal

Surgical endoscopy
ISSN: 1432-2218
Titre abrégé: Surg Endosc
Pays: Germany
ID NLM: 8806653

Informations de publication

Date de publication:
09 2023
Historique:
received: 26 12 2022
accepted: 17 06 2023
medline: 31 8 2023
pubmed: 29 6 2023
entrez: 28 6 2023
Statut: ppublish

Résumé

Zenker's diverticulum is a rare disease that affects quality of life due to dysphagia and regurgitation. This condition can be treated by various surgical or endoscopic methods. Patients treated for Zenker's diverticulum in three centers in the south of France between 2014 and 2019 were included. The primary objective was clinical efficacy. Secondary objectives were technical success, morbidities, recurrences, and need for a new procedure. One hundred forty-four patients with a total of one hundred sixty-five procedures performed were included. A significant difference was found between the different groups in terms of clinical success (97% for open surgery versus 79% for rigid endoscopy versus 90% for flexible endoscopy, p = 0.009). Technical failure occurred more frequently in the rigid endoscopy group than in the flexible endoscopy and surgical groups (p = 0.014). Median procedure duration, median time to resumption of feeding, and hospital discharge were statistically shorter for endoscopies than for open surgery. On the other hand, more recurrences occurred in patients treated by endoscopy than those treated by surgery, and more reinterventions were required. Flexible endoscopy appears to be as effective and safe as open surgery in the treatment of Zenker's diverticulum. Endoscopy allows a shorter hospital stay at the expense of a higher risk of recurrence of symptoms. It could be used as an alternative to open surgery for the treatment of Zenker's diverticulum, especially in frail patients.

Sections du résumé

BACKGROUND AND STUDY AIM
Zenker's diverticulum is a rare disease that affects quality of life due to dysphagia and regurgitation. This condition can be treated by various surgical or endoscopic methods.
PATIENTS AND METHOD
Patients treated for Zenker's diverticulum in three centers in the south of France between 2014 and 2019 were included. The primary objective was clinical efficacy. Secondary objectives were technical success, morbidities, recurrences, and need for a new procedure.
RESULTS
One hundred forty-four patients with a total of one hundred sixty-five procedures performed were included. A significant difference was found between the different groups in terms of clinical success (97% for open surgery versus 79% for rigid endoscopy versus 90% for flexible endoscopy, p = 0.009). Technical failure occurred more frequently in the rigid endoscopy group than in the flexible endoscopy and surgical groups (p = 0.014). Median procedure duration, median time to resumption of feeding, and hospital discharge were statistically shorter for endoscopies than for open surgery. On the other hand, more recurrences occurred in patients treated by endoscopy than those treated by surgery, and more reinterventions were required.
CONCLUSION
Flexible endoscopy appears to be as effective and safe as open surgery in the treatment of Zenker's diverticulum. Endoscopy allows a shorter hospital stay at the expense of a higher risk of recurrence of symptoms. It could be used as an alternative to open surgery for the treatment of Zenker's diverticulum, especially in frail patients.

Identifiants

pubmed: 37380740
doi: 10.1007/s00464-023-10225-4
pii: 10.1007/s00464-023-10225-4
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7064-7072

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Franz Rudler (F)

Gastroenterology Department, CHU Montpellier, Montpellier, France. f-rudler@chu-montpellier.fr.

Guillaume Pineton de Chambrun (G)

Gastroenterology Department, CHU Montpellier, Montpellier, France.

Benjamin Lallemant (B)

ORL Department, CHU Nimes, Nîmes, France.

Renaud Garrel (R)

ORL Department, CHU Montpellier, Montpellier, France.

Philippe Pouderoux (P)

Gastroenterology Department, CHU Nimes, Nimes, France.

Mohamed Ramdani (M)

Gastroenterology Department, CH Beziers, Béziers, France.

Ludovic Caillo (L)

Gastroenterology Department, CHU Nimes, Nimes, France.

Christophe Reynaud (C)

ORL Department, CHU Nimes, Nîmes, France.

Jean-Christophe Valats (JC)

Gastroenterology Department, CHU Montpellier, Montpellier, France.

Pierre Blanc (P)

Gastroenterology Department, CHU Montpellier, Montpellier, France.

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