Galactose-functionalized injectable thermosensitive microgels for target specific uptake in hepatoma cells.


Journal

Journal of biomaterials applications
ISSN: 1530-8022
Titre abrégé: J Biomater Appl
Pays: England
ID NLM: 8813912

Informations de publication

Date de publication:
08 2023
Historique:
medline: 8 8 2023
pubmed: 29 6 2023
entrez: 29 6 2023
Statut: ppublish

Résumé

Microgels acts as a potential candidate for responsive composite materials, which has been favored by scientists because of its excellent colloid stability, easy integration, and most of their surface area can be used as support after modification. Specififically, microgels are fascinating capable of maintaining good biocompatibility and controlled-release in vivo and making the possible for applications in biomaterials and biomedicines. Besides, in the process of microgel synthesis, some targeting factors can be combined to achieve the purpose of cell targeting and uptake. Therefore, how to fundamentally design microgels is an urgent problem to be solved. In this study, we design and synthesize an injectable microgel P(DEGMA-

Identifiants

pubmed: 37382366
doi: 10.1177/08853282231184645
doi:

Substances chimiques

Microgels 0
Galactose X2RN3Q8DNE
Gels 0
Doxorubicin 80168379AG

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

243-253

Auteurs

Qianru Zhang (Q)

Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, China.

Lili Zhu (L)

Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, China.

Tianyi Zhang (T)

Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, China.

Jing Quan (J)

Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, China.
Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor(Guangxi Medical University), Ministry of Education, Guangxi Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Guangxi, China.

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Classifications MeSH