Does Dietary Polyunsaturated Fatty Acid Intake Associate With Bone Mineral Density and Limb Structural Changes in Early Rheumatoid Arthritis?
Bone mineral density
arm fat mass
early rheumatoid arthritis
inflammation
polyunsaturated fatty acids
Journal
Nutrition and metabolic insights
ISSN: 1178-6388
Titre abrégé: Nutr Metab Insights
Pays: United States
ID NLM: 101550186
Informations de publication
Date de publication:
2023
2023
Historique:
received:
24
02
2023
accepted:
28
04
2023
pubmed:
29
6
2023
medline:
29
6
2023
entrez:
29
6
2023
Statut:
epublish
Résumé
Rheumatoid arthritis (RA) is an inflammatory disease that can result in bone erosion, lean mass lowering, and increase of fat mass without changes in body weight. The dietary consumption of polyunsaturated fatty acids (PUFAs) has been assessed in many studies due to their potential anti-inflammatory effect. The aim of this research was to identify if dietary intake of PUFAs associates with bone mineral density (BMD) and limb structural changes in early rheumatoid arthritis (ERA) compared to a population-based control group. The study was conducted because previous results have been insufficient. The study group consisted of 83 ERA patients and 321 control subjects. A dual-energy X-Ray absorptiometry (DXA) machine was used to measure hip, lumbar spine, and radius BMD, as well as arm and leg fat, lean, and bone mass. Dietary habits and inflammatory markers were assessed to evaluate the effects to BMD and limb structural changes. In ERA subjects, higher dietary consumption of PUFAs was associated with a decrease in arm fat mass (b -28.17, Balanced nutrition is essential. Consuming PUFAs could be beneficial in ERA preventing structural changes to hands, but additional research is needed.
Sections du résumé
Background
UNASSIGNED
Rheumatoid arthritis (RA) is an inflammatory disease that can result in bone erosion, lean mass lowering, and increase of fat mass without changes in body weight. The dietary consumption of polyunsaturated fatty acids (PUFAs) has been assessed in many studies due to their potential anti-inflammatory effect.
Aim
UNASSIGNED
The aim of this research was to identify if dietary intake of PUFAs associates with bone mineral density (BMD) and limb structural changes in early rheumatoid arthritis (ERA) compared to a population-based control group. The study was conducted because previous results have been insufficient.
Methods
UNASSIGNED
The study group consisted of 83 ERA patients and 321 control subjects. A dual-energy X-Ray absorptiometry (DXA) machine was used to measure hip, lumbar spine, and radius BMD, as well as arm and leg fat, lean, and bone mass. Dietary habits and inflammatory markers were assessed to evaluate the effects to BMD and limb structural changes.
Results
UNASSIGNED
In ERA subjects, higher dietary consumption of PUFAs was associated with a decrease in arm fat mass (b -28.17,
Conclusion
UNASSIGNED
Balanced nutrition is essential. Consuming PUFAs could be beneficial in ERA preventing structural changes to hands, but additional research is needed.
Identifiants
pubmed: 37383545
doi: 10.1177/11786388231176169
pii: 10.1177_11786388231176169
pmc: PMC10293524
doi:
Types de publication
Journal Article
Langues
eng
Pagination
11786388231176169Informations de copyright
© The Author(s) 2023.
Déclaration de conflit d'intérêts
The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.