Influence of HIV-1 Genomic RNA on the Formation of Gag Biomolecular Condensates.


Journal

Journal of molecular biology
ISSN: 1089-8638
Titre abrégé: J Mol Biol
Pays: Netherlands
ID NLM: 2985088R

Informations de publication

Date de publication:
15 08 2023
Historique:
received: 02 02 2023
revised: 18 06 2023
accepted: 20 06 2023
medline: 14 8 2023
pubmed: 30 6 2023
entrez: 29 6 2023
Statut: ppublish

Résumé

Biomolecular condensates (BMCs) play an important role in the replication of a growing number of viruses, but many important mechanistic details remain to be elucidated. Previously, we demonstrated that the pan-retroviral nucleocapsid (NC) and HIV-1 pr55

Identifiants

pubmed: 37385580
pii: S0022-2836(23)00289-9
doi: 10.1016/j.jmb.2023.168190
pii:
doi:

Substances chimiques

gag Gene Products, Human Immunodeficiency Virus 0
RNA, Viral 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

168190

Subventions

Organisme : CIHR
ID : FRN-162447
Pays : Canada
Organisme : CIHR
ID : PJT-178165
Pays : Canada

Commentaires et corrections

Type : UpdateOf

Informations de copyright

Copyright © 2023. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Anne Monette (A)

Lady Davis Institute at the Jewish General Hospital, Montréal, Québec H3T 1E2, Canada.

Meijuan Niu (M)

Lady Davis Institute at the Jewish General Hospital, Montréal, Québec H3T 1E2, Canada.

Rebecca Kaddis Maldonado (RK)

Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States.

Jordan Chang (J)

Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States.

Gregory S Lambert (GS)

Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States.

John M Flanagan (JM)

Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States.

Alan Cochrane (A)

Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Leslie J Parent (LJ)

Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, United States. Electronic address: lparent@pennstatehealth.psu.edu.

Andrew J Mouland (AJ)

Lady Davis Institute at the Jewish General Hospital, Montréal, Québec H3T 1E2, Canada; Department of Medicine, McGill University, Montréal, Québec H4A 3J1, Canada. Electronic address: andrew.mouland@mcgill.ca.

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Classifications MeSH