Discovery of insulin 100 years on.

Clinical Pharmacology General Diabetes Medical History

Journal

Postgraduate medical journal
ISSN: 1469-0756
Titre abrégé: Postgrad Med J
Pays: England
ID NLM: 0234135

Informations de publication

Date de publication:
30 Jun 2023
Historique:
received: 14 03 2022
accepted: 25 04 2022
medline: 3 7 2023
pubmed: 30 6 2023
entrez: 30 6 2023
Statut: ppublish

Résumé

The discovery of insulin 100 years ago ranks among the greatest medical achievements ever. This sparked a revolution of scientific discovery and therapeutic intervention to treat people suffering with diabetes. A light was shone for other areas of medicine to illuminate what was possible with detailed scientific endeavour. There followed a range of firsts leading to the current time in which we now know more about this peptide hormone than almost any other protein in existence. This has allowed therapeutic advancement from a positon of knowledge leading to stunning innovation. This innovation is likely to lead to more physiological insulin replacement reducing the disease burden to individuals and society as whole.

Identifiants

pubmed: 37389580
pii: 7211536
doi: 10.1136/postgradmedj-2022-141651
doi:

Substances chimiques

Insulin 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

661-668

Subventions

Organisme : Eli Lilly, Novo Nordisk, Takeda, Novartis, AstraZeneca, Sanofi, Dexcom and Pfizer

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Auteurs

David Russell-Jones (D)

CEDAR, Royal Surrey County Hospital, Guildford, UK.
Diabetes & Endocrinology, University of Surrey, Guildford, UK.

Zosanglura Bawlchhim (Z)

CEDAR, Royal Surrey County Hospital, Guildford, UK.

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Classifications MeSH