Recent advances on Pestalotiopsis genus: chemistry, biological activities, structure-activity relationship, and biosynthesis.
Bioactivity
Biosynthesis
Chemical constituents
Pestalotiopsis
Journal
Archives of pharmacal research
ISSN: 1976-3786
Titre abrégé: Arch Pharm Res
Pays: Korea (South)
ID NLM: 8000036
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
22
09
2022
accepted:
21
06
2023
medline:
12
7
2023
pubmed:
30
6
2023
entrez:
30
6
2023
Statut:
ppublish
Résumé
Strains of the fungal genus Pestalotiopsis are reported as large promising sources of structurally varied biologically active metabolites. Many bioactive secondary metabolites with diverse structural features have been derived from Pestalotiopsis. Moreover, some of these compounds can potentially be developed into lead compounds. Herein, we have systematically reviewed the chemical constituents and bioactivities of the fungal genus Pestalotiopsis, covering a period ranging from January 2016 to December 2022. As many as 307 compounds, including terpenoids, coumarins, lactones, polyketides, and alkaloids, were isolated during this period. Furthermore, for the benefit of readers, the biosynthesis and potential medicinal value of these new compounds are also discussed in this review. Finally, the perspectives and directions for future research and the potential applications of the new compounds are summarized in various tables.
Identifiants
pubmed: 37389739
doi: 10.1007/s12272-023-01453-2
pii: 10.1007/s12272-023-01453-2
doi:
Substances chimiques
Alkaloids
0
Lactones
0
Polyketides
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
449-499Subventions
Organisme : National Natural Science Foundation of China
ID : No. 31900293
Organisme : Department of Science and Technology of Sichuan Province
ID : 2022NSFSC0109
Organisme : the Open Project of Sichuan Industrial Institute of Antibiotics, Chengdu University
ID : ARRLKF20-04
Organisme : Sichuan Science and Technology Program
ID : 2022YFS0624
Informations de copyright
© 2023. The Pharmaceutical Society of Korea.
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