Clinical, microbiological and osteoimmunological findings in different peri-implant conditions - A cross-sectional study.
Fusobacterium
Porphyromonas gingivalis
cytokines
dental implants
microbiota
notch signaling
peri-implantitis
peri-mucositis
Journal
Clinical oral implants research
ISSN: 1600-0501
Titre abrégé: Clin Oral Implants Res
Pays: Denmark
ID NLM: 9105713
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
revised:
08
05
2023
received:
18
08
2022
accepted:
20
06
2023
medline:
6
9
2023
pubmed:
1
7
2023
entrez:
1
7
2023
Statut:
ppublish
Résumé
The aim of this study was to assess the prevalence of certain microbiota and their potential correlation with clinical parameters, expression of proinflammatory cytokines, Notch signalling pathway molecules and bone remodelling mediators among different peri-implant conditions. Included participants had at least one dental implant minimally 1 year in function. They were divided into peri-implantitis (PI), peri-implant mucositis (PM) and healthy implants (HIs) groups. Prevalence of P. ginigvalis, Fusobacterium spp., EBV and C. albicans was detected in participants' crevicular fluid (CF) using quantitative real-time polymerase chain reaction, different markers' expression, as well as clinical data, were correlated with the microbial presence. CF samples taken from one chosen implant from each of the 102 participants were analyzed. Significantly higher levels of P. gingivalis were found in PI compared with HI (p = .012) and PM (p = .026). Fusobacterium spp. was also more prevalent in PI (p = .041) and PM (0.008) than in HI. P. gingivalis was a predictor of PPDi (p = .011, R P. gingivalis appears to be involved in the osteolysis in patients with PI, while the positive correlation of its level with Notch 2 expression in patients with PM suggests a potential involvement of P. gingivalis in the progression of PM into PI.
Substances chimiques
Dental Implants
0
Types de publication
Journal Article
Langues
eng
Pagination
958-966Subventions
Organisme : 451-03-68/2022-14/200129
Organisme : Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja
Informations de copyright
© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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