Optical coherence tomography angiography findings in pediatric patients with graves ophthalmopathy.
Optical coherence tomography angiography
Pediatric graves ophthalmopathy
Retinal nerve fiber layer
Journal
International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
03
02
2023
accepted:
22
06
2023
medline:
18
9
2023
pubmed:
1
7
2023
entrez:
1
7
2023
Statut:
ppublish
Résumé
The aim of this study was to evaluate peripapillary, macular microvascular structure, and retinal nerve fiber layer (RNFL) thickness profile in children with Graves Ophthalmopathy (GO). Thirty-six eyes of 18 children with GO were prospectively compared with 40 eyes of 20-age and sex-matched controls. The severity and activity of the disease were evaluated according to the criteria of the European Group on Graves' Ophthalmopathy (EUGOGO) and Clinical Activity Score (CAS). After complete ophthalmologic and endocrinologic examination, all patients underwent optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) measurements. Retinal nerve fiber layer (RNFL) thickness, macular superficial capillary plexus (SCP), deep capillary plexus (DCP), foveal avascular zone (FAZ) area, acircularity index (AI) of the FAZ and peripapillary microvascular structure were analyzed. The mean age was 12.1 ± 2.4 years in the GO group and 11.2 ± 2.6 years in healthy control group (p = 0.11). Duration of disease was 8.9 ± 4.2 months in the GO group. All patients in GO group had mild and inactive ophthalmopathy. In temporal inferior quadrant, RNFL thickness was significantly thinner in the GO group compared to the control group (p = 0.03). No significant difference was seen between groups both peripapillary and macular microvascular structure (all p > 0.05). GO has no effect on optic nerve thickness, peripapillary and macular vascular parameters except inferior temporal RNFL in children.
Identifiants
pubmed: 37392258
doi: 10.1007/s10792-023-02769-0
pii: 10.1007/s10792-023-02769-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3609-3614Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature B.V.
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