Evaluation of near-infrared Raman spectroscopy in the differentiation of cortical bone, trabecular bone, and Bio-Oss bone graft: an ex-vivo study.


Journal

Oral surgery, oral medicine, oral pathology and oral radiology
ISSN: 2212-4411
Titre abrégé: Oral Surg Oral Med Oral Pathol Oral Radiol
Pays: United States
ID NLM: 101576782

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 29 12 2022
revised: 18 05 2023
accepted: 20 05 2023
medline: 10 11 2023
pubmed: 3 7 2023
entrez: 2 7 2023
Statut: ppublish

Résumé

We evaluated the ability of near-infrared Raman spectroscopy (near-IR RS) to differentiate among cortical bone, trabecular bone, and Bio-Oss, a bovinebone-based graft material. We obtained a thinly sliced section of the mandible to collect cortical and trabecular bone samples and placed compacted Bio-Oss bone graft into a partially edentulous mandible in a dry human skull to obtain a comparable Bio-Oss sample. We performed near-IR RS of the 3 samples and evaluated the resultant Raman spectra to evaluate their differences. We identified 3 sets of spectroscopic markers that differentiated Bio-Oss from human bone. The first consisted of significant shifts in the location of the 960 cm Near-IR RS can reliably differentiate human cortical and trabecular bone from Bio-Oss via 3 sets of spectral markers associated with mineral crystallinity, carbonate content, and collagen content that differ significantly between them. Integrating this modality into dental practice may assist in implant treatment planning.

Identifiants

pubmed: 37394288
pii: S2212-4403(23)00460-1
doi: 10.1016/j.oooo.2023.05.015
pii:
doi:

Substances chimiques

Bio-Oss 0
Bone Substitutes 0
Minerals 0
Collagen 9007-34-5
Carbonates 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

632-639

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Anusha Vaddi (A)

Section of Oral and Maxillofacial Radiology, Division of Oral and Maxillofacial Diagnostic Sciences, UConn School of Dental Medicine, UConn Health, Farmington, CT, USA. Electronic address: Vaddia@vcu.edu.

Aditya Tadinada (A)

Section of Oral and Maxillofacial Radiology, Division of Oral and Maxillofacial Diagnostic Sciences, UConn School of Dental Medicine, UConn Health, Farmington, CT, USA.

Alan Lurie (A)

Section of Oral and Maxillofacial Radiology, Division of Oral and Maxillofacial Diagnostic Sciences, UConn School of Dental Medicine, UConn Health, Farmington, CT, USA.

Alix Deymier (A)

Department of Biomedical Engineering, UConn School of Dental Medicine, UConn Health, Farmington, CT, USA.

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Classifications MeSH